Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 800 |
| Chain | Residue |
| A | THR15 |
| A | GLN16 |
| A | TYR17 |
| A | VAL33 |
| A | THR224 |
| A | ALA226 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 801 |
| Chain | Residue |
| A | NA802 |
| A | NA802 |
| A | NA802 |
| A | NA803 |
| A | ACT804 |
| A | LEU114 |
| A | LEU118 |
| A | PHE250 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 802 |
| Chain | Residue |
| A | ACT801 |
| A | ACT801 |
| A | ACT801 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 803 |
| Chain | Residue |
| A | ACT801 |
| A | ACT804 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 804 |
| Chain | Residue |
| A | TYR57 |
| A | HOH414 |
| A | ACT801 |
| A | NA803 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 3OX A 500 |
| Chain | Residue |
| A | GLN16 |
| A | ASP35 |
| A | GLY37 |
| A | TYR80 |
| A | SER81 |
| A | THR82 |
| A | PRO115 |
| A | PHE116 |
| A | LEU118 |
| A | PHE121 |
| A | GLN132 |
| A | ASP223 |
| A | GLY225 |
| A | ALA226 |
| A | SER227 |
| A | TYR228 |
| A | SER230 |
| A | HIS298 |
| A | HOH410 |
| A | HOH413 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 3OW B 501 |
| Chain | Residue |
| B | THR15 |
| B | TYR17 |
| B | VAL33 |
| B | ASP35 |
| B | GLY37 |
| B | TYR80 |
| B | SER81 |
| B | THR82 |
| B | PHE121 |
| B | ASP223 |
| B | THR224 |
| B | GLY225 |
| B | ALA226 |
| B | SER227 |
| B | TYR228 |
| B | SER230 |
| B | HIS298 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV |
| Chain | Residue | Details |
| A | VAL32-VAL43 | |
| A | ALA220-GLY231 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20927107","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2493678","evidenceCode":"ECO:0000269"}]} |
