Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 600 |
| Chain | Residue |
| A | SER168 |
| B | SER168 |
| B | HOH1136 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 601 |
| Chain | Residue |
| A | ASN268 |
| A | GLN278 |
| A | PHE279 |
| A | SER280 |
| A | ASN378 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 603 |
| Chain | Residue |
| A | TYR111 |
| A | PRO161 |
| A | ILE163 |
| A | EDO625 |
| A | HOH640 |
| A | HOH1070 |
| A | TRP107 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 604 |
| Chain | Residue |
| A | ASN136 |
| A | MSE139 |
| A | ALA140 |
| A | LYS143 |
| A | GLU194 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 606 |
| Chain | Residue |
| A | ALA45 |
| A | ASN48 |
| A | HOH675 |
| B | ALA496 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 607 |
| Chain | Residue |
| A | SER428 |
| A | GLU432 |
| A | EDO626 |
| A | HOH1133 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 608 |
| Chain | Residue |
| A | SER318 |
| A | ARG459 |
| A | ASP461 |
| A | LYS462 |
| A | ACT609 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 609 |
| Chain | Residue |
| A | SER318 |
| A | GLU320 |
| A | ARG459 |
| A | ACT608 |
| A | HOH1029 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 612 |
| Chain | Residue |
| A | VAL277 |
| A | GLN278 |
| A | ARG284 |
| A | HOH684 |
| A | HOH1146 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 613 |
| Chain | Residue |
| A | LEU94 |
| A | LEU95 |
| A | VAL96 |
| A | TYR506 |
| A | HOH701 |
| A | HOH779 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 625 |
| Chain | Residue |
| A | TYR111 |
| A | ILE163 |
| A | GLN167 |
| A | ACT603 |
| A | HOH638 |
| A | HOH865 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 626 |
| Chain | Residue |
| A | VAL396 |
| A | ALA427 |
| A | SER428 |
| A | ACT607 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 627 |
| Chain | Residue |
| A | THR334 |
| A | ASN335 |
| A | ASP354 |
| A | HOH1248 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 628 |
| Chain | Residue |
| A | LEU281 |
| A | ASN282 |
| A | ASP376 |
| B | HOH1310 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 630 |
| Chain | Residue |
| A | ASN503 |
| A | GLN504 |
| A | HOH688 |
| A | HOH1291 |
| B | GLN504 |
| B | HOH1091 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 631 |
| Chain | Residue |
| A | ASN118 |
| A | ARG146 |
| A | THR164 |
| A | HOH851 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 632 |
| Chain | Residue |
| A | TYR384 |
| A | GLN405 |
| A | GLN412 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 634 |
| Chain | Residue |
| A | ASN48 |
| A | HOH1048 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 636 |
| Chain | Residue |
| A | GLN495 |
| A | HOH694 |
| A | HOH807 |
| A | HOH832 |
| A | HOH898 |
| A | HOH1031 |
| B | ARG284 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 602 |
| Chain | Residue |
| B | LYS181 |
| B | TYR225 |
| B | GLY232 |
| B | TYR236 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 605 |
| Chain | Residue |
| B | ASN136 |
| B | LYS143 |
| B | GLU194 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 610 |
| Chain | Residue |
| B | ALA45 |
| B | ASN48 |
| B | HOH939 |
| A | GLN174 |
| A | ALA496 |
| A | PRO498 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 611 |
| Chain | Residue |
| B | SER428 |
| B | GLU432 |
| B | TRP435 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 614 |
| Chain | Residue |
| B | LEU94 |
| B | LEU95 |
| B | VAL96 |
| B | HOH912 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 615 |
| Chain | Residue |
| B | PRO161 |
| B | LYS162 |
| B | VAL175 |
| B | SER176 |
| B | HOH1275 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 616 |
| Chain | Residue |
| A | ASP354 |
| B | ASP185 |
| B | ILE189 |
| B | TYR225 |
| B | TYR236 |
| B | HOH964 |
| B | HOH1320 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 617 |
| Chain | Residue |
| B | ASN48 |
| B | HOH1107 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 618 |
| Chain | Residue |
| B | VAL277 |
| B | GLN278 |
| B | ARG284 |
| B | HOH775 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 619 |
| Chain | Residue |
| B | SER280 |
| B | LEU281 |
| B | ASN282 |
| B | ASP376 |
| B | HOH1474 |
| B | HOH1476 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 620 |
| Chain | Residue |
| B | ILE310 |
| B | PRO311 |
| B | GLY357 |
| B | TYR358 |
| B | HOH1391 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 621 |
| Chain | Residue |
| B | THR326 |
| B | GLU328 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 622 |
| Chain | Residue |
| B | TRP107 |
| B | TYR111 |
| B | HOH801 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 623 |
| Chain | Residue |
| B | HIS205 |
| B | GLU252 |
| B | THR254 |
| B | GLY271 |
| site_id | DC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EDO B 624 |
| Chain | Residue |
| B | TYR74 |
| B | MSE75 |
| B | GLY77 |
| B | ALA79 |
| B | TYR88 |
| B | PHE91 |
| B | LEU94 |
| B | TRP476 |
| B | TYR480 |
| B | HOH878 |
| B | HOH1049 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 629 |
| Chain | Residue |
| B | VAL396 |
| B | ASN397 |
| B | GLY400 |
| B | SER428 |
| site_id | DC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 633 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 635 |
| Chain | Residue |
| B | ASN118 |
| B | GLN122 |
| B | ARG146 |
| B | THR164 |
