3OTI
Crystal Structure of CalG3, Calicheamicin Glycostyltransferase, TDP and calicheamicin T0 bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008194 | molecular_function | UDP-glycosyltransferase activity |
| A | 0016758 | molecular_function | hexosyltransferase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0046527 | molecular_function | glucosyltransferase activity |
| B | 0008194 | molecular_function | UDP-glycosyltransferase activity |
| B | 0016758 | molecular_function | hexosyltransferase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0046527 | molecular_function | glucosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TYD A 377 |
| Chain | Residue |
| A | GLY10 |
| A | LEU271 |
| A | HIS284 |
| A | GLY286 |
| A | GLY287 |
| A | GLY288 |
| A | THR289 |
| A | C0T378 |
| A | HOH380 |
| A | HOH388 |
| A | HOH416 |
| A | GLY195 |
| A | HOH472 |
| A | HOH496 |
| A | HOH498 |
| A | GLY218 |
| A | THR219 |
| A | ILE220 |
| A | GLY249 |
| A | TRP268 |
| A | THR269 |
| A | PRO270 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C0T A 378 |
| Chain | Residue |
| A | PRO7 |
| A | GLY10 |
| A | PHE60 |
| A | GLN88 |
| A | GLN116 |
| A | GLY117 |
| A | GLN137 |
| A | SER138 |
| A | TRP140 |
| A | GLY286 |
| A | GLY287 |
| A | ASP308 |
| A | PHE310 |
| A | GLN311 |
| A | TYD377 |
| A | HOH527 |
| A | HOH689 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 379 |
| Chain | Residue |
| A | TYR194 |
| A | GLY195 |
| A | LEU271 |
| A | HIS272 |
| A | HOH498 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TYD B 377 |
| Chain | Residue |
| B | GLY10 |
| B | GLY195 |
| B | GLY218 |
| B | THR219 |
| B | ILE220 |
| B | GLY249 |
| B | TRP268 |
| B | THR269 |
| B | PRO270 |
| B | LEU271 |
| B | HIS284 |
| B | GLY286 |
| B | GLY287 |
| B | GLY288 |
| B | THR289 |
| B | C0T378 |
| B | HOH384 |
| B | HOH391 |
| B | HOH413 |
| B | HOH453 |
| B | HOH512 |
| B | HOH547 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE C0T B 378 |
| Chain | Residue |
| B | PRO7 |
| B | GLY10 |
| B | PHE60 |
| B | LEU82 |
| B | GLN88 |
| B | ILE89 |
| B | GLN116 |
| B | GLY117 |
| B | GLN137 |
| B | SER138 |
| B | TRP140 |
| B | ILE220 |
| B | GLY286 |
| B | GLY287 |
| B | ASP308 |
| B | PHE310 |
| B | GLN311 |
| B | TYD377 |
| B | HOH481 |
| B | HOH666 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 379 |
| Chain | Residue |
| B | TYR194 |
| B | GLY195 |
| B | LEU271 |
| B | HIS272 |
| B | HOH547 |
