3OP1
Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003919 | molecular_function | FMN adenylyltransferase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006747 | biological_process | FAD biosynthetic process |
A | 0006771 | biological_process | riboflavin metabolic process |
A | 0008531 | molecular_function | riboflavin kinase activity |
A | 0009231 | biological_process | riboflavin biosynthetic process |
A | 0009398 | biological_process | FMN biosynthetic process |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
B | 0003919 | molecular_function | FMN adenylyltransferase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006747 | biological_process | FAD biosynthetic process |
B | 0006771 | biological_process | riboflavin metabolic process |
B | 0008531 | molecular_function | riboflavin kinase activity |
B | 0009231 | biological_process | riboflavin biosynthetic process |
B | 0009398 | biological_process | FMN biosynthetic process |
B | 0016301 | molecular_function | kinase activity |
B | 0016310 | biological_process | phosphorylation |
B | 0016779 | molecular_function | nucleotidyltransferase activity |
C | 0003919 | molecular_function | FMN adenylyltransferase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0006747 | biological_process | FAD biosynthetic process |
C | 0006771 | biological_process | riboflavin metabolic process |
C | 0008531 | molecular_function | riboflavin kinase activity |
C | 0009231 | biological_process | riboflavin biosynthetic process |
C | 0009398 | biological_process | FMN biosynthetic process |
C | 0016301 | molecular_function | kinase activity |
C | 0016310 | biological_process | phosphorylation |
C | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 311 |
Chain | Residue |
A | TYR25 |
A | HIS30 |
A | HIS33 |
A | SER163 |
A | SER164 |
A | HOH343 |
A | HOH361 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 312 |
Chain | Residue |
A | VAL152 |
A | PRO153 |
A | PRO154 |
A | VAL155 |
A | ILE162 |
A | HOH387 |
A | GLY32 |
A | GLY126 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PEG A 314 |
Chain | Residue |
A | LEU64 |
A | PRO66 |
A | HOH390 |
B | HIS195 |
C | LYS159 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 315 |
Chain | Residue |
A | ASP260 |
A | ARG302 |
A | HOH370 |
C | ARG38 |
C | ASN41 |
C | GLU88 |
C | HOH364 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ACY A 316 |
Chain | Residue |
A | LYS61 |
A | ASP70 |
A | ARG168 |
A | TYR217 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 317 |
Chain | Residue |
A | GLU58 |
A | HIS74 |
A | PRO78 |
A | ARG215 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 318 |
Chain | Residue |
A | GLY24 |
A | TYR25 |
A | MSE54 |
A | TYR129 |
A | HOH320 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PEG A 319 |
Chain | Residue |
A | PHE72 |
A | ARG215 |
A | HOH375 |
B | CL306 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL B 313 |
Chain | Residue |
A | GLY180 |
A | PRO186 |
B | PHE247 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 311 |
Chain | Residue |
B | HIS30 |
B | HIS33 |
B | SER163 |
B | SER164 |
B | HOH399 |
B | HOH400 |
site_id | BC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 312 |
Chain | Residue |
B | ASP285 |
B | GLN289 |
C | LYS42 |
site_id | BC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 306 |
Chain | Residue |
A | PEG319 |
B | PEG314 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE PEG B 314 |
Chain | Residue |
A | LEU212 |
B | PRO69 |
B | PHE72 |
B | ARG215 |
B | CL306 |
B | HOH398 |
site_id | BC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 315 |
Chain | Residue |
B | ARG199 |
B | THR282 |
B | LYS283 |
B | PHE284 |
site_id | BC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE GOL B 316 |
Chain | Residue |
B | SER59 |
B | LYS61 |
site_id | BC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE PEG B 317 |
Chain | Residue |
B | GLY24 |
B | MSE54 |
B | PHE102 |
B | PHE110 |
B | TYR129 |
B | THR130 |
B | PHE131 |
B | GLY132 |
B | HOH370 |
B | HOH375 |
B | HOH387 |
site_id | BC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 C 311 |
Chain | Residue |
C | TYR25 |
C | HIS30 |
C | HIS33 |
C | LYS161 |
C | SER163 |
C | SER164 |
C | GOL314 |
C | HOH329 |
site_id | BC9 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL C 312 |
Chain | Residue |
C | HIS30 |
C | GLY32 |
C | GLY126 |
C | PHE127 |
C | VAL152 |
C | PRO153 |
C | PRO154 |
C | VAL155 |
C | LYS161 |
C | HOH330 |
site_id | CC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL C 313 |
Chain | Residue |
C | GLY24 |
C | TYR25 |
C | MSE54 |
C | TYR129 |
C | HOH338 |
C | HOH342 |
site_id | CC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL C 314 |
Chain | Residue |
C | ASP128 |
C | TYR129 |
C | SO4311 |
C | HOH370 |
site_id | CC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL C 315 |
Chain | Residue |
C | PRO69 |
C | PHE72 |
C | VAL211 |
C | ARG215 |
site_id | CC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL C 316 |
Chain | Residue |
C | TYR25 |
C | PHE56 |
C | HIS74 |
C | ARG81 |
C | HOH366 |