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3OO3

Crystal Structure of the Orf6* (CYP165D3) Monooxygenase Involved in Teicoplanin Biosynthesis

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0016746molecular_functionacyltransferase activity
A0016757molecular_functionglycosyltransferase activity
A0016874molecular_functionligase activity
A0020037molecular_functionheme binding
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues25
DetailsBINDING SITE FOR RESIDUE HEM A 400
ChainResidue
ALEU79
ALEU267
APRO276
AALA277
AARG279
AALA324
APHE325
AGLY326
AILE329
AHIS330
ACYS332
AGLN80
AILE333
AGLY334
AHOH409
AHOH453
AHOH518
AHOH526
AHIS87
AARG91
ATYR98
AASN223
AMET226
AALA227
AGLN230

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGIHHCIG
ChainResidueDetails
APHE325-GLY334

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PDB entries from 2024-11-13

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