Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033353 | biological_process | S-adenosylmethionine cycle |
| B | 0004013 | molecular_function | adenosylhomocysteinase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0033353 | biological_process | S-adenosylmethionine cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD A 501 |
| Chain | Residue |
| A | THR206 |
| A | GLU292 |
| A | ILE293 |
| A | ASP294 |
| A | CYS297 |
| A | THR324 |
| A | THR325 |
| A | GLY326 |
| A | ASN327 |
| A | ILE330 |
| A | ILE348 |
| A | THR207 |
| A | GLY349 |
| A | HIS350 |
| A | ASN397 |
| A | HIS404 |
| A | HOH502 |
| A | 3AD504 |
| A | HOH517 |
| A | HOH521 |
| A | HOH555 |
| A | HOH655 |
| A | THR208 |
| A | HOH716 |
| A | HOH722 |
| B | GLN466 |
| B | LYS479 |
| B | TYR483 |
| B | HOH690 |
| A | ASN240 |
| A | GLY269 |
| A | GLY271 |
| A | ASP272 |
| A | VAL273 |
| A | THR291 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 3AD A 504 |
| Chain | Residue |
| A | LEU61 |
| A | HIS62 |
| A | THR64 |
| A | GLN66 |
| A | THR67 |
| A | ASP139 |
| A | GLU205 |
| A | LYS235 |
| A | ASP239 |
| A | LEU395 |
| A | THR402 |
| A | HIS404 |
| A | MET409 |
| A | NAD501 |
| A | HOH804 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 507 |
| Chain | Residue |
| A | GLN66 |
| A | THR402 |
| A | GLY403 |
| A | HIS404 |
| A | HOH554 |
| A | HOH783 |
| site_id | AC4 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE NAD B 502 |
| Chain | Residue |
| A | LYS479 |
| A | TYR483 |
| A | HOH654 |
| B | THR206 |
| B | THR207 |
| B | THR208 |
| B | ASN240 |
| B | GLY269 |
| B | GLY271 |
| B | ASP272 |
| B | VAL273 |
| B | THR291 |
| B | GLU292 |
| B | ILE293 |
| B | ASP294 |
| B | CYS297 |
| B | THR324 |
| B | THR325 |
| B | GLY326 |
| B | ASN327 |
| B | ILE330 |
| B | ILE348 |
| B | GLY349 |
| B | HIS350 |
| B | ASN397 |
| B | HIS404 |
| B | HOH491 |
| B | 3AD505 |
| B | HOH508 |
| B | HOH523 |
| B | HOH640 |
| B | HOH645 |
| B | HOH704 |
| B | HOH771 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TRS B 503 |
| Chain | Residue |
| A | HOH602 |
| B | VAL474 |
| B | GLU475 |
| B | TYR478 |
| B | HOH581 |
| B | HOH665 |
| B | HOH779 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 3AD B 505 |
| Chain | Residue |
| B | GLN66 |
| B | THR67 |
| B | ASP139 |
| B | GLU205 |
| B | LYS235 |
| B | ASP239 |
| B | LEU395 |
| B | THR402 |
| B | HIS404 |
| B | MET409 |
| B | PHE413 |
| B | NAD502 |
| B | HOH707 |
| B | HIS62 |
| B | THR64 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 506 |
| Chain | Residue |
| B | GLN66 |
| B | THR402 |
| B | GLY403 |
| B | HIS404 |
| B | HOH489 |
| B | HOH605 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDhAAAAI |
| Chain | Residue | Details |
| A | SER85-ILE99 | |
| site_id | PS00739 |
| Number of Residues | 18 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKvavVaGYGdVGKGcaA |
| Chain | Residue | Details |
| A | GLY262-ALA279 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
