Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033353 | biological_process | S-adenosylmethionine cycle |
| B | 0004013 | molecular_function | adenosylhomocysteinase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0033353 | biological_process | S-adenosylmethionine cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD A 501 |
| Chain | Residue |
| A | THR206 |
| A | GLU292 |
| A | ILE293 |
| A | ASP294 |
| A | CYS297 |
| A | THR324 |
| A | THR325 |
| A | GLY326 |
| A | ASN327 |
| A | ILE330 |
| A | ILE348 |
| A | THR207 |
| A | GLY349 |
| A | HIS350 |
| A | LEU395 |
| A | ASN397 |
| A | HIS404 |
| A | ADE506 |
| A | HOH512 |
| A | HOH555 |
| A | HOH576 |
| A | HOH591 |
| A | THR208 |
| A | HOH655 |
| A | HOH696 |
| A | HOH715 |
| B | GLN466 |
| B | LYS479 |
| B | TYR483 |
| A | ASN240 |
| A | GLY269 |
| A | GLY271 |
| A | ASP272 |
| A | VAL273 |
| A | THR291 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TRS A 505 |
| Chain | Residue |
| A | THR460 |
| A | VAL474 |
| A | GLU475 |
| A | TYR478 |
| A | HOH643 |
| A | HOH719 |
| B | HOH1073 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADE A 506 |
| Chain | Residue |
| A | HIS62 |
| A | THR64 |
| A | GLN66 |
| A | THR67 |
| A | THR402 |
| A | GLY403 |
| A | HIS404 |
| A | MET409 |
| A | PHE413 |
| A | NAD501 |
| A | HOH754 |
| A | HOH937 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 509 |
| Chain | Residue |
| A | THR402 |
| A | GLY403 |
| A | HIS404 |
| A | HOH537 |
| A | HOH653 |
| site_id | AC5 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD B 502 |
| Chain | Residue |
| A | LYS479 |
| A | TYR483 |
| B | THR206 |
| B | THR207 |
| B | THR208 |
| B | ASP239 |
| B | ASN240 |
| B | GLY269 |
| B | GLY271 |
| B | ASP272 |
| B | VAL273 |
| B | THR291 |
| B | GLU292 |
| B | ILE293 |
| B | ASP294 |
| B | CYS297 |
| B | THR324 |
| B | THR325 |
| B | GLY326 |
| B | ASN327 |
| B | ILE330 |
| B | ILE348 |
| B | GLY349 |
| B | HIS350 |
| B | LEU395 |
| B | ASN397 |
| B | HIS404 |
| B | HOH487 |
| B | ADE507 |
| B | HOH536 |
| B | HOH553 |
| B | HOH613 |
| B | HOH627 |
| B | HOH656 |
| B | HOH702 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TRS B 503 |
| Chain | Residue |
| B | HOH718 |
| B | HOH1102 |
| A | HOH1072 |
| B | VAL474 |
| B | GLU475 |
| B | TYR478 |
| B | HOH530 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TRS B 504 |
| Chain | Residue |
| B | GLU361 |
| B | VAL366 |
| B | LYS367 |
| B | ARG368 |
| B | TRP378 |
| B | HOH568 |
| B | HOH682 |
| B | HOH1221 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADE B 507 |
| Chain | Residue |
| B | THR64 |
| B | GLN66 |
| B | THR67 |
| B | THR402 |
| B | HIS404 |
| B | MET409 |
| B | PHE413 |
| B | NAD502 |
| B | HOH738 |
| B | HOH755 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 508 |
| Chain | Residue |
| B | THR402 |
| B | GLY403 |
| B | HIS404 |
| B | HOH856 |
| B | HOH1103 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDhAAAAI |
| Chain | Residue | Details |
| A | SER85-ILE99 | |
| site_id | PS00739 |
| Number of Residues | 18 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKvavVaGYGdVGKGcaA |
| Chain | Residue | Details |
| A | GLY262-ALA279 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | THR64 | |
| A | ASN327 | |
| A | ILE348 | |
| A | ASN397 | |
| B | THR64 | |
| B | ASP139 | |
| B | GLU205 | |
| B | THR206 | |
| B | LYS235 | |
| B | ASP239 | |
| B | ASN240 | |
| A | ASP139 | |
| B | GLY269 | |
| B | GLU292 | |
| B | ASN327 | |
| B | ILE348 | |
| B | ASN397 | |
| A | GLU205 | |
| A | THR206 | |
| A | LYS235 | |
| A | ASP239 | |
| A | ASN240 | |
| A | GLY269 | |
| A | GLU292 | |
