3OJ7

Crystal structure of a histidine triad family protein from entamoeba histolytica, bound to sulfate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0043530	molecular_function	adenosine 5'-monophosphoramidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 114

Chain	Residue
A	CYS5
A	CYS8
A	HIS47
A	HIS97

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 115

Chain	Residue
A	HIS101
A	HOH116
A	ASN86
A	GLY92
A	GLN93
A	THR94
A	HIS99

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Functional Information from PROSITE/UniProt

site_id	PS00892
Number of Residues	19
Details	HIT_1 HIT domain signature. NigedAgQtVkHIHFHILG

Chain	Residue	Details
A	ASN86-GLY104

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Tele-AMP-histidine intermediate => ECO:0000250|UniProtKB:P49773

Chain	Residue	Details
A	HIS99

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0007744|PDB:3OJ7, ECO:0007744|PDB:3OMF, ECO:0007744|PDB:3OXK

Chain	Residue	Details
A	CYS5
A	CYS8
A	HIS47
A	HIS97

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:25945711, ECO:0007744|PDB:3OMF

Chain	Residue	Details
A	ASP31
A	ASN86
A	GLY92
A	THR94
A	HIS99
A	HIS101

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