Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000165 | biological_process | MAPK cascade |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004707 | molecular_function | MAP kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0006468 | biological_process | protein phosphorylation |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0035556 | biological_process | intracellular signal transduction |
B | 0000165 | biological_process | MAPK cascade |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004707 | molecular_function | MAP kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005634 | cellular_component | nucleus |
B | 0005737 | cellular_component | cytoplasm |
B | 0006468 | biological_process | protein phosphorylation |
B | 0016301 | molecular_function | kinase activity |
B | 0016310 | biological_process | phosphorylation |
B | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE 1N1 A 1000 |
Chain | Residue |
A | GLY32 |
A | MET110 |
A | GLY111 |
A | ASN116 |
A | ASP169 |
A | PHE170 |
A | VAL39 |
A | ALA52 |
A | LYS54 |
A | GLU72 |
A | LEU76 |
A | LEU105 |
A | THR107 |
A | LEU109 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE 1N1 A 2000 |
Chain | Residue |
A | ASP146 |
A | ILE147 |
A | ILE148 |
A | ARG150 |
A | TRP198 |
A | MET199 |
A | ASN202 |
A | VAL205 |
B | ARG190 |
B | ILE194 |
B | ALA256 |
site_id | AC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE 1N1 B 1000 |
Chain | Residue |
B | GLY32 |
B | VAL39 |
B | ALA52 |
B | LYS54 |
B | GLU72 |
B | LEU76 |
B | LEU105 |
B | THR107 |
B | HIS108 |
B | LEU109 |
B | MET110 |
B | ASN116 |
B | ASP169 |
B | PHE170 |
site_id | AC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 1N1 B 2000 |
Chain | Residue |
A | ARG190 |
B | ASP146 |
B | ILE147 |
B | ILE148 |
B | ARG150 |
B | TRP198 |
B | MET199 |
B | ASN202 |
B | VAL205 |
B | SO43001 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 3001 |
Chain | Residue |
B | ARG150 |
B | LYS153 |
B | 1N12000 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 3004 |
Chain | Residue |
B | ARG74 |
B | HIS78 |
B | TYR324 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 25 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGSGAYGSVCsSydvksglki.........AVKK |
Chain | Residue | Details |
A | VAL31-LYS55 | |
site_id | PS01351 |
Number of Residues | 104 |
Details | MAPK MAP kinase signature. FqsiihakrtyRElrllkhmkhenviglldvftpatsleefndvylvthlmgadlnnivkcqkltddhvqfliyqilrglkyihsadiih.........RDlKpsnlavnedC |
Chain | Residue | Details |
A | PHE60-CYS163 | |