3ODC
Human PARP-1 zinc finger 2 (Zn2) bound to DNA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | CYS125 |
| A | CYS128 |
| A | HIS159 |
| A | CYS162 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 701 |
| Chain | Residue |
| B | CYS125 |
| B | CYS128 |
| B | HIS159 |
| B | CYS162 |
Functional Information from PROSITE/UniProt
| site_id | PS00347 |
| Number of Residues | 38 |
| Details | ZF_PARP_1 Zinc finger poly(ADP-ribose) polymerase (PARP)-type signature. CKgCmekIeKgqvRlskkmvdpekpqlgmidrWYHpgC |
| Chain | Residue | Details |
| A | CYS125-CYS162 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00264","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21233213","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22683995","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ODC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ODE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4AV1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 90 |
| Details | Zinc finger: {"description":"PARP-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00264","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
