3OD2
E. coli NikR soaked with excess nickel ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
| A | 0001217 | molecular_function | DNA-binding transcription repressor activity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005667 | cellular_component | transcription regulator complex |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0010045 | biological_process | response to nickel cation |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 2000143 | biological_process | negative regulation of DNA-templated transcription initiation |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
| B | 0001217 | molecular_function | DNA-binding transcription repressor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005667 | cellular_component | transcription regulator complex |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0010045 | biological_process | response to nickel cation |
| B | 0016151 | molecular_function | nickel cation binding |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 2000143 | biological_process | negative regulation of DNA-templated transcription initiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 134 |
| Chain | Residue |
| A | HIS87 |
| A | HIS89 |
| A | CYS95 |
| B | VAL72 |
| B | HIS76 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 135 |
| Chain | Residue |
| B | HOH156 |
| A | MET1 |
| A | HOH149 |
| A | HOH150 |
| B | HOH145 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 136 |
| Chain | Residue |
| A | HIS125 |
| A | HOH147 |
| A | HOH148 |
| B | HIS125 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 137 |
| Chain | Residue |
| A | HIS78 |
| A | HIS110 |
| A | ASP114 |
| A | HOH144 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 138 |
| Chain | Residue |
| A | HIS79 |
| A | HOH156 |
| A | HOH161 |
| A | HOH162 |
| A | HOH171 |
| B | HIS92 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 139 |
| Chain | Residue |
| A | HIS123 |
| A | HOH153 |
| A | HOH164 |
| B | PRO130 |
| B | HOH165 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 3CM B 134 |
| Chain | Residue |
| A | ARG3 |
| A | LEU19 |
| A | SER20 |
| A | ARG23 |
| A | TYR25 |
| A | ILE35 |
| B | GLU43 |
| B | GLY124 |
| B | HIS125 |
| B | LEU126 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 135 |
| Chain | Residue |
| A | HIS76 |
| B | HIS87 |
| B | HIS89 |
| B | CYS95 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 136 |
| Chain | Residue |
| B | HIS78 |
| B | HIS110 |
| B | ASP114 |
| B | HOH146 |
| B | HOH148 |
| B | HOH158 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI B 137 |
| Chain | Residue |
| A | HOH160 |
| A | HOH165 |
| B | HIS123 |
| B | HOH149 |
| B | HOH168 |
| B | HOH169 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NI B 138 |
| Chain | Residue |
| A | HIS92 |
| B | HIS79 |
| B | ASP80 |
| B | HOH160 |
| B | HOH161 |
| B | HOH162 |
| B | HOH164 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 139 |
| Chain | Residue |
| A | HOH157 |
| A | HOH158 |
| B | MET1 |
| B | HOH142 |
| B | HOH170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS76 | |
| A | HIS87 | |
| A | HIS89 | |
| A | CYS95 | |
| B | HIS76 | |
| B | HIS87 | |
| B | HIS89 | |
| B | CYS95 |
