3OBI
Crystal structure of a formyltetrahydrofolate deformylase (NP_949368) from RHODOPSEUDOMONAS PALUSTRIS CGA009 at 1.95 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 300 |
| Chain | Residue |
| A | TYR107 |
| A | ARG110 |
| A | ASP134 |
| A | HOH759 |
| B | GLY132 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | HOH1209 |
| B | ASP113 |
| A | ARG253 |
| A | ASP257 |
| A | ARG260 |
| A | HOH1077 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | ARG89 |
| A | HIS270 |
| A | ASP273 |
| A | ARG274 |
| A | VAL275 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | THR87 |
| A | ARG88 |
| A | ARG89 |
| A | HIS115 |
| A | LEU271 |
| A | HOH618 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 310 |
| Chain | Residue |
| A | SER11 |
| A | HIS46 |
| A | LEU277 |
| A | ASN278 |
| A | GLY279 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 311 |
| Chain | Residue |
| A | PRO144 |
| A | GLN153 |
| A | HOH702 |
| A | HOH1328 |
| D | HIS142 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 320 |
| Chain | Residue |
| A | ARG127 |
| A | GLU128 |
| A | HOH1270 |
| D | ASN146 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 327 |
| Chain | Residue |
| A | ALA249 |
| A | HOH906 |
| A | HOH1277 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 301 |
| Chain | Residue |
| B | PHE143 |
| B | HOH403 |
| B | HOH1075 |
| B | HOH1094 |
| C | ASP137 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 304 |
| Chain | Residue |
| B | ASP99 |
| B | THR129 |
| B | PHE130 |
| B | SER131 |
| B | HOH1137 |
| B | HOH1174 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 307 |
| Chain | Residue |
| B | HIS268 |
| B | TYR269 |
| B | ASP287 |
| B | HOH1033 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 312 |
| Chain | Residue |
| B | HIS194 |
| B | SER196 |
| B | THR221 |
| D | LEU198 |
| D | PRO199 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 313 |
| Chain | Residue |
| B | ARG66 |
| B | TRP80 |
| B | HIS81 |
| B | MSE82 |
| B | HOH932 |
| B | HOH1120 |
| B | HOH1241 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 319 |
| Chain | Residue |
| B | ASP137 |
| B | HOH548 |
| B | HOH658 |
| B | HOH1103 |
| C | PHE143 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 322 |
| Chain | Residue |
| B | ASP238 |
| B | ARG261 |
| B | ARG265 |
| B | HOH797 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 326 |
| Chain | Residue |
| B | HIS208 |
| B | ASP212 |
| D | GLU43 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 328 |
| Chain | Residue |
| B | ARG89 |
| B | HIS270 |
| B | ASP273 |
| B | ARG274 |
| B | VAL275 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 302 |
| Chain | Residue |
| C | ARG66 |
| C | TRP80 |
| C | HIS81 |
| C | MSE82 |
| C | HOH736 |
| C | HOH1216 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 306 |
| Chain | Residue |
| A | LEU198 |
| A | PRO199 |
| C | HIS194 |
| C | SER196 |
| C | THR221 |
| C | HOH1045 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 314 |
| Chain | Residue |
| C | LEU106 |
| C | ARG110 |
| C | ASP134 |
| D | EDO318 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 316 |
| Chain | Residue |
| C | THR9 |
| C | ARG89 |
| C | HIS270 |
| C | ASP273 |
| C | ARG274 |
| C | VAL275 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 317 |
| Chain | Residue |
| C | ASP113 |
| C | LEU114 |
| C | ARG265 |
| C | HOH1061 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 321 |
| Chain | Residue |
| A | PRO248 |
| A | HOH585 |
| C | GLU43 |
| C | HOH696 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 323 |
| Chain | Residue |
| C | ASN29 |
| C | SER64 |
| C | GLY68 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 324 |
| Chain | Residue |
| C | ARG89 |
| C | ASP167 |
| C | HIS270 |
| C | HOH1178 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 325 |
| Chain | Residue |
| C | ILE177 |
| C | LEU178 |
| C | ASP230 |
| C | HOH526 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 303 |
| Chain | Residue |
| A | HIS142 |
| D | PRO144 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 315 |
| Chain | Residue |
| D | ARG89 |
| D | HIS270 |
| D | ASP273 |
| D | ARG274 |
| D | VAL275 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 318 |
| Chain | Residue |
| C | ARG110 |
| C | GLY132 |
| C | EDO314 |
| D | TYR107 |
| D | ARG110 |
| D | ASP134 |
| D | HOH555 |
