3OA8

Diheme SoxAX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009055	molecular_function	electron transfer activity
A	0016669	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
A	0019417	biological_process	sulfur oxidation
A	0020037	molecular_function	heme binding
A	0070069	cellular_component	cytochrome complex
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
C	0009055	molecular_function	electron transfer activity
C	0016669	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
C	0019417	biological_process	sulfur oxidation
C	0020037	molecular_function	heme binding
C	0070069	cellular_component	cytochrome complex
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
E	0009055	molecular_function	electron transfer activity
E	0016669	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor
E	0019417	biological_process	sulfur oxidation
E	0020037	molecular_function	heme binding
E	0070069	cellular_component	cytochrome complex
F	0009055	molecular_function	electron transfer activity
F	0020037	molecular_function	heme binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEC A 401

Chain	Residue
A	PHE181
A	THR212
A	TRP216
A	MET233
A	CSS236
A	TYR237
A	GLN239
A	MET240
A	LYS274
A	HOH536
A	HOH826
A	SER182
A	CYS183
A	CYS186
A	HIS187
A	ILE194
A	GLN197
A	ALA198
A	LEU199

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC B 401

Chain	Residue
A	PHE181
B	CYS125
B	CYS128
B	HIS129
B	LEU141
B	PRO143
B	LEU145
B	TYR148
B	LYS165
B	VAL166
B	SER176
B	MET178
B	PRO179
B	VAL195
B	HOH222
B	HOH372
F	GLU74

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 209

Chain	Residue
B	ASN70
B	PRO71
D	ASN70
D	PRO71
F	ASN70
F	PRO71

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC C 401

Chain	Residue
C	SER182
C	CYS183
C	CYS186
C	HIS187
C	ILE194
C	GLN197
C	LEU199
C	THR212
C	TRP216
C	ARG232
C	MET233
C	CSS236
C	TYR237
C	GLN239
C	MET240
C	LYS274
C	HOH835

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEC D 401

Chain	Residue
B	GLU74
C	PHE181
D	GLY123
D	ASN124
D	CYS125
D	CYS128
D	HIS129
D	LEU141
D	PRO143
D	LEU145
D	TYR148
D	ARG152
D	LYS165
D	VAL166
D	SER176
D	MET178
D	HOH227
D	HOH576

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC E 401

Chain	Residue
E	SER182
E	CYS183
E	CYS186
E	HIS187
E	ILE194
E	GLN197
E	THR212
E	MET213
E	TRP216
E	ARG232
E	MET233
E	CSS236
E	TYR237
E	MET240
E	LYS274
E	HOH346
E	HOH452

---

site_id	AC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEC F 401

Chain	Residue
F	LEU141
F	PRO143
F	LEU145
F	TYR148
F	ARG152
F	LYS165
F	VAL166
F	LEU173
F	SER176
F	SER177
F	MET178
F	PRO179
F	PHE181
F	HOH241
F	HOH529
F	HOH592
D	GLU74
E	PHE181
F	CYS125
F	CYS128
F	HIS129

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"PubMed","id":"21592966","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"description":"covalent","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21592966","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21592966","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q939U1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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