Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 A 100 |
Chain | Residue |
A | ARG14 |
A | GLY16 |
A | GLY17 |
A | HOH132 |
A | HOH138 |
B | GLY16 |
B | HOH124 |
B | HOH128 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PO4 B 100 |
Chain | Residue |
B | GLU65 |
B | GLY68 |
B | HOH162 |
B | ARG14 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PO4 A 101 |
Chain | Residue |
A | MET36 |
A | ASN37 |
A | HOH112 |
B | PRO39 |
B | GLY40 |
B | HOH139 |
B | HOH166 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 102 |
Chain | Residue |
A | GLY48 |
A | GLY49 |
A | PHE53 |
A | HOH119 |
B | THR91 |
B | GLN92 |
B | HOH164 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ACT A 103 |
Chain | Residue |
A | ARG14 |
A | GLY17 |
A | PRO44 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ACT A 104 |
Chain | Residue |
A | LYS20 |
A | GLU21 |
A | ASN83 |
A | HOH147 |
A | HOH149 |
site_id | AC7 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE K2A A 200 |
Chain | Residue |
A | ASP25 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
A | HOH106 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP29 |
B | ASP30 |
B | VAL32 |
B | GLY48 |
B | GLY49 |
B | VAL82 |
B | ILE84 |
B | HOH105 |
B | HOH112 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
Chain | Residue | Details |
A | ALA22-LEU33 | |