3O8Q

1.45 Angstrom Resolution Crystal Structure of Shikimate 5-Dehydrogenase (aroE) from Vibrio cholerae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0019632	biological_process	shikimate metabolic process
A	0050661	molecular_function	NADP binding
B	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
B	0019632	biological_process	shikimate metabolic process
B	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 279

Chain	Residue
A	GLN32
A	HOH501
A	HOH502
A	HOH503
A	HOH504
A	HOH505

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 280

Chain	Residue
A	HOH463
A	THR65
A	VAL66
A	LYS69

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 281

Chain	Residue
A	VAL66
A	PRO67
A	PHE68
A	LYS69
A	GLU70
A	HOH493

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 282

Chain	Residue
A	GLY262
A	THR263
A	LYS264
A	HOH288
A	HOH488
A	HOH506

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site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE A 283

Chain	Residue
A	THR80
A	GLU81
A	ARG82
A	GLU108
A	GLN145
A	HOH393
A	HOH416
A	HOH454
A	HOH473
B	GLU172

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 2

Chain	Residue
B	ARG74
B	ALA76
B	HOH399
B	HOH464
B	HOH516

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site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 279

Chain	Residue
B	VAL66
B	PRO67
B	PHE68
B	LYS69
B	GLU70
B	HOH352
B	HOH507
B	HOH517

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