3O8B
Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0019087 | biological_process | symbiont-mediated transformation of host cell |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0019087 | biological_process | symbiont-mediated transformation of host cell |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 800 |
| Chain | Residue |
| A | HOH2 |
| A | CYS97 |
| A | CYS99 |
| A | CYS145 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 825 |
| Chain | Residue |
| A | LYS210 |
| A | SER211 |
| A | HOH974 |
| A | HOH1059 |
| A | PRO205 |
| A | THR206 |
| A | GLY207 |
| A | SER208 |
| A | GLY209 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1 |
| Chain | Residue |
| A | THR254 |
| A | GLY255 |
| A | THR269 |
| A | HOH860 |
| A | HOH1021 |
| A | HOH1188 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 800 |
| Chain | Residue |
| B | CYS97 |
| B | CYS99 |
| B | CYS145 |
| B | HOH824 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 825 |
| Chain | Residue |
| B | PRO205 |
| B | THR206 |
| B | GLY207 |
| B | SER208 |
| B | GLY209 |
| B | LYS210 |
| B | SER211 |
| B | HOH664 |
| B | HOH887 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2 |
| Chain | Residue |
| B | VAL232 |
| B | THR254 |
| B | GLY255 |
| B | THR269 |
| B | HOH964 |
| B | HOH979 |
| B | HOH1021 |
