3O7B
Crystal structure of Archaeoglobus Fulgidus Nep1 bound to S-adenosylhomocysteine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006364 | biological_process | rRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0019843 | molecular_function | rRNA binding |
| A | 0032259 | biological_process | methylation |
| A | 0042254 | biological_process | ribosome biogenesis |
| A | 0070037 | molecular_function | rRNA (pseudouridine) methyltransferase activity |
| A | 0070475 | biological_process | rRNA base methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TYR A 220 |
| Chain | Residue |
| A | ARG153 |
| A | SER191 |
| A | LEU192 |
| A | GLY193 |
| A | ARG205 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH A 301 |
| Chain | Residue |
| A | GLY169 |
| A | PHE171 |
| A | GLY174 |
| A | PHE176 |
| A | VAL190 |
| A | SER191 |
| A | LEU192 |
| A | GLY193 |
| A | GLU195 |
| A | SER196 |
| A | TYR197 |
| A | SER199 |
| A | VAL202 |
| A | HOH238 |
| A | HOH320 |
| A | HOH383 |
| A | PHE147 |
| A | ARG148 |
| A | GLU149 |
| A | ILE168 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:21087996, ECO:0007744|PDB:3O7B |
| Chain | Residue | Details |
| A | PHE147 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00554, ECO:0000305|PubMed:21087996, ECO:0007744|PDB:3O7B |
| Chain | Residue | Details |
| A | GLY169 | |
| A | GLY174 | |
| A | LEU192 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Interaction with substrate rRNA => ECO:0000255|HAMAP-Rule:MF_00554 |
| Chain | Residue | Details |
| A | ARG61 | |
| A | ARG99 | |
| A | ARG102 | |
| A | ARG106 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Stabilizes Arg-61 => ECO:0000255|HAMAP-Rule:MF_00554 |
| Chain | Residue | Details |
| A | ASP63 |
