3NZP
Crystal Structure of the Biosynthetic Arginine decarboxylase SpeA from Campylobacter jejuni, Northeast Structural Genomics Consortium Target BR53
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006527 | biological_process | L-arginine catabolic process |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| A | 0008792 | molecular_function | arginine decarboxylase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006527 | biological_process | L-arginine catabolic process |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0008792 | molecular_function | arginine decarboxylase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP A 701 |
| Chain | Residue |
| A | PRO84 |
| A | GLY274 |
| A | GLU320 |
| A | SER321 |
| A | GLY322 |
| A | ARG323 |
| A | TYR519 |
| B | CYS483 |
| A | LYS86 |
| A | VAL87 |
| A | ASN132 |
| A | HIS231 |
| A | HIS233 |
| A | SER236 |
| A | GLN237 |
| A | GLY273 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 702 |
| Chain | Residue |
| A | ASN11 |
| A | GLU278 |
| A | ARG288 |
| A | PHE324 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP B 701 |
| Chain | Residue |
| A | CYS483 |
| B | PRO84 |
| B | LYS86 |
| B | ASN132 |
| B | HIS231 |
| B | HIS233 |
| B | SER236 |
| B | GLY273 |
| B | GLY274 |
| B | GLU320 |
| B | SER321 |
| B | GLY322 |
| B | ARG323 |
| B | TYR519 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 702 |
| Chain | Residue |
| A | GLU546 |
| B | HIS616 |
| B | HIS617 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 703 |
| Chain | Residue |
| B | ARG39 |
| B | LYS44 |
| B | GLY45 |
| B | PRO335 |
| B | ASN443 |
| B | LEU606 |
| B | LYS607 |
Functional Information from PROSITE/UniProt
| site_id | PS00878 |
| Number of Residues | 19 |
| Details | ODR_DC_2_1 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. YPlKVNqypgFVknLvklG |
| Chain | Residue | Details |
| A | TYR83-GLY101 |
