3NZ4
Crystal Structure of a Taxus Phenylalanine Aminomutase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006558 | biological_process | L-phenylalanine metabolic process |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0009698 | biological_process | phenylpropanoid metabolic process |
| A | 0009800 | biological_process | cinnamic acid biosynthetic process |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0009821 | biological_process | alkaloid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016841 | molecular_function | ammonia-lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016869 | molecular_function | intramolecular aminotransferase activity |
| A | 0042617 | biological_process | paclitaxel biosynthetic process |
| A | 0045548 | molecular_function | phenylalanine ammonia-lyase activity |
| A | 0051289 | biological_process | protein homotetramerization |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006558 | biological_process | L-phenylalanine metabolic process |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0009698 | biological_process | phenylpropanoid metabolic process |
| B | 0009800 | biological_process | cinnamic acid biosynthetic process |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0009821 | biological_process | alkaloid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016841 | molecular_function | ammonia-lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016869 | molecular_function | intramolecular aminotransferase activity |
| B | 0042617 | biological_process | paclitaxel biosynthetic process |
| B | 0045548 | molecular_function | phenylalanine ammonia-lyase activity |
| B | 0051289 | biological_process | protein homotetramerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TCA B 699 |
| Chain | Residue |
| A | GLN319 |
| A | ARG325 |
| B | TYR80 |
| B | LEU104 |
| B | MDO176 |
| B | ASN355 |
| B | PHE371 |
| B | GLU455 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TCA A 699 |
| Chain | Residue |
| A | GLY87 |
| A | LEU104 |
| A | MDO176 |
| A | PHE371 |
| B | GLN319 |
| B | ARG325 |
| A | TYR80 |
Functional Information from PROSITE/UniProt
| site_id | PS00488 |
| Number of Residues | 17 |
| Details | PAL_HISTIDASE Phenylalanine and histidine ammonia-lyases signature. GSVSASGDLiPLAyiaG |
| Chain | Residue | Details |
| A | GLY171-LEU189 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q68G84","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q68G84","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21361343","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NZ4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P11544","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"2,3-didehydroalanine (Ser)","evidences":[{"source":"UniProtKB","id":"Q68G84","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"5-imidazolinone (Ala-Gly)","evidences":[{"source":"UniProtKB","id":"Q68G84","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
