3NZ2
Crystal Structure of Hexapeptide-Repeat containing-Acetyltransferase VCA0836 Complexed with Acetyl Co Enzyme A from Vibrio cholerae O1 biovar eltor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008374 | molecular_function | O-acyltransferase activity |
| A | 0016407 | molecular_function | acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008374 | molecular_function | O-acyltransferase activity |
| B | 0016407 | molecular_function | acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0008374 | molecular_function | O-acyltransferase activity |
| C | 0016407 | molecular_function | acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0008374 | molecular_function | O-acyltransferase activity |
| D | 0016407 | molecular_function | acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0008374 | molecular_function | O-acyltransferase activity |
| E | 0016407 | molecular_function | acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0008374 | molecular_function | O-acyltransferase activity |
| F | 0016407 | molecular_function | acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0008374 | molecular_function | O-acyltransferase activity |
| G | 0016407 | molecular_function | acetyltransferase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016746 | molecular_function | acyltransferase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0008374 | molecular_function | O-acyltransferase activity |
| H | 0016407 | molecular_function | acetyltransferase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016746 | molecular_function | acyltransferase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0008374 | molecular_function | O-acyltransferase activity |
| I | 0016407 | molecular_function | acetyltransferase activity |
| I | 0016740 | molecular_function | transferase activity |
| I | 0016746 | molecular_function | acyltransferase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0008374 | molecular_function | O-acyltransferase activity |
| J | 0016407 | molecular_function | acetyltransferase activity |
| J | 0016740 | molecular_function | transferase activity |
| J | 0016746 | molecular_function | acyltransferase activity |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0008374 | molecular_function | O-acyltransferase activity |
| K | 0016407 | molecular_function | acetyltransferase activity |
| K | 0016740 | molecular_function | transferase activity |
| K | 0016746 | molecular_function | acyltransferase activity |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0008374 | molecular_function | O-acyltransferase activity |
| L | 0016407 | molecular_function | acetyltransferase activity |
| L | 0016740 | molecular_function | transferase activity |
| L | 0016746 | molecular_function | acyltransferase activity |
| L | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ACO A 195 |
| Chain | Residue |
| A | TYR109 |
| A | HOH732 |
| A | HOH993 |
| C | PHE81 |
| C | ASN83 |
| C | TRP137 |
| C | GLY139 |
| C | GLY140 |
| C | ALA157 |
| C | ALA158 |
| C | LEU171 |
| A | HIS113 |
| C | GLY173 |
| C | GLY174 |
| C | LEU180 |
| C | ARG181 |
| A | ASN145 |
| A | ASN163 |
| A | THR175 |
| A | PRO176 |
| A | HOH204 |
| A | HOH460 |
| A | HOH463 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 196 |
| Chain | Residue |
| A | LEU40 |
| A | GLU42 |
| A | ARG45 |
| B | SER27 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 197 |
| Chain | Residue |
| A | PHE15 |
| A | GLY17 |
| A | TRP123 |
| A | HOH198 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ACO A 193 |
| Chain | Residue |
| A | ASN83 |
| A | LEU101 |
| A | ILE102 |
| A | GLY103 |
| A | TRP137 |
| A | GLY139 |
| A | GLY140 |
| A | ALA157 |
| A | ALA158 |
| A | LEU171 |
| A | GLY174 |
| A | LEU180 |
| A | HOH217 |
| B | TYR109 |
| B | HIS113 |
| B | ASN145 |
| B | ASN163 |
| B | THR175 |
| B | PRO176 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 196 |
| Chain | Residue |
| B | HIS113 |
| B | THR125 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 197 |
| Chain | Residue |
| B | GLY17 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY B 198 |
| Chain | Residue |
| B | ASP98 |
| B | HIS99 |
| B | ASP135 |
| E | ARG153 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ACO C 195 |
| Chain | Residue |
| B | ASN83 |
| B | GLY103 |
| B | PRO104 |
| B | TRP137 |
| B | GLY139 |
| B | GLY140 |
| B | ALA158 |
| B | GLY174 |
| B | LEU180 |
| B | ARG181 |
| B | HOH194 |
| B | HOH818 |
| B | HOH970 |
| C | LEU89 |
| C | TYR109 |
| C | ALA111 |
| C | HIS113 |
| C | LEU115 |
| C | ASN163 |
| C | THR175 |
| C | PRO176 |
| C | HOH202 |
| C | HOH641 |
| C | HOH969 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 196 |
| Chain | Residue |
| C | ALA177 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 197 |
| Chain | Residue |
| B | ASN159 |
| B | HOH268 |
| C | ASN159 |
| C | THR175 |
| C | HOH199 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ACO D 195 |
| Chain | Residue |
| D | HOH601 |
| E | ALA111 |
| E | HIS113 |
| E | ASN145 |
| E | VAL161 |
| E | ASN163 |
| E | THR175 |
| D | ASN83 |
| D | GLY103 |
| D | PRO104 |
| D | TRP137 |
| D | GLY139 |
| D | GLY140 |
| D | ALA157 |
| D | ALA158 |
| D | GLY174 |
| D | LEU180 |
| D | HOH196 |
| D | HOH200 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY D 197 |
| Chain | Residue |
| D | LYS59 |
| D | HIS79 |
| E | GLN121 |
| E | TRP123 |
| site_id | BC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ACO E 195 |
| Chain | Residue |
| E | ASN83 |
| E | GLY103 |
| E | PRO104 |
| E | TRP137 |
| E | GLY139 |
| E | GLY140 |
| E | ALA157 |
| E | ALA158 |
| E | GLY174 |
| E | LEU180 |
| E | ARG181 |
| E | HOH202 |
| E | HOH203 |
| E | HOH207 |
| E | HOH688 |
| F | LEU89 |
| F | TYR109 |
| F | HIS113 |
| F | ASN163 |
| F | THR175 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 196 |
| Chain | Residue |
| E | GLU42 |
| E | ARG45 |
| E | GLN49 |
| E | VAL62 |
| E | GLN63 |
| E | PRO64 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL E 193 |
| Chain | Residue |
| E | HIS79 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY F 196 |
| Chain | Residue |
| D | GLN121 |
| D | ALA122 |
| D | TRP123 |
| F | HIS79 |
| site_id | BC8 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ACO F 195 |
| Chain | Residue |
| D | LEU89 |
| D | TYR109 |
| D | HIS113 |
| D | LEU115 |
| D | ASN163 |
| D | THR175 |
| D | PRO176 |
| F | ASN83 |
| F | PRO104 |
| F | TRP137 |
| F | GLY139 |
| F | GLY140 |
| F | ALA157 |
| F | ALA158 |
| F | LEU171 |
| F | GLY174 |
| F | ARG181 |
| F | HOH204 |
| F | HOH530 |
| F | HOH646 |
| F | HOH916 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL F 197 |
| Chain | Residue |
| F | GLU42 |
| F | ARG45 |
| F | GLN49 |
| F | CYS61 |
| F | VAL62 |
| F | GLN63 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY G 196 |
| Chain | Residue |
| G | GLU42 |
| G | ARG45 |
| G | GLN49 |
| G | CYS61 |
| G | VAL62 |
| G | GLN63 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU1 G 197 |
| Chain | Residue |
| G | HIS14 |
| G | PHE15 |
| G | TRP123 |
| G | GLU124 |
| G | THR125 |
| site_id | CC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ACO H 195 |
| Chain | Residue |
| G | TYR109 |
| G | HIS113 |
| G | ASN145 |
| G | ASN163 |
| G | THR175 |
| G | HOH695 |
| H | PHE81 |
| H | ASN83 |
| H | LEU101 |
| H | ILE102 |
| H | TRP137 |
| H | GLY139 |
| H | GLY140 |
| H | ALA157 |
| H | ALA158 |
| H | GLY173 |
| H | GLY174 |
| H | LEU180 |
| H | ARG181 |
| H | HOH193 |
| H | HOH354 |
| H | HOH506 |
| H | HOH975 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL H 196 |
| Chain | Residue |
| H | HIS14 |
| H | SER114 |
| H | ILE126 |
| site_id | CC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ACO I 195 |
| Chain | Residue |
| G | ASN83 |
| G | GLY103 |
| G | PRO104 |
| G | GLY139 |
| G | GLY140 |
| G | ALA157 |
| G | ALA158 |
| G | GLY174 |
| G | ARG181 |
| G | HOH199 |
| G | HOH777 |
| I | LEU89 |
| I | TYR109 |
| I | HIS113 |
| I | ASN145 |
| I | ASN163 |
| I | THR175 |
| I | HOH210 |
| L | LYS11 |
| site_id | CC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ACO I 193 |
| Chain | Residue |
| H | LEU89 |
| H | ALA111 |
| H | HIS113 |
| H | LEU115 |
| H | VAL161 |
| H | ASN163 |
| H | THR175 |
| I | PHE81 |
| I | ASN83 |
| I | GLY103 |
| I | TRP137 |
| I | GLY139 |
| I | GLY140 |
| I | ALA157 |
| I | ALA158 |
| I | GLY174 |
| I | ARG181 |
| I | HOH199 |
| I | HOH691 |
| I | HOH864 |
| I | HOH973 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACY I 196 |
| Chain | Residue |
| I | LYS59 |
| I | HIS79 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL J 196 |
| Chain | Residue |
| J | ASN37 |
| site_id | CC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ACO J 195 |
| Chain | Residue |
| J | ASN83 |
| J | GLY103 |
| J | TRP137 |
| J | ILE138 |
| J | GLY139 |
| J | GLY140 |
| J | ALA157 |
| J | ALA158 |
| J | GLY174 |
| J | ARG181 |
| J | HOH903 |
| J | HOH1001 |
| J | HOH1018 |
| K | LEU89 |
| K | TYR109 |
| K | ALA111 |
| K | ASN163 |
| K | THR175 |
| K | PRO176 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BU1 K 196 |
| Chain | Residue |
| K | HIS58 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY K 197 |
| Chain | Residue |
| K | ARG45 |
| K | GLN49 |
| K | VAL62 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY K 198 |
| Chain | Residue |
| G | ALA43 |
| G | GLU44 |
| K | GLU44 |
| K | LEU48 |
| K | GLU51 |
| site_id | DC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ACO L 195 |
| Chain | Residue |
| I | GLU7 |
| I | HOH624 |
| K | GLY103 |
| K | TRP137 |
| K | GLY139 |
| K | GLY140 |
| K | ALA157 |
| K | ALA158 |
| K | GLY174 |
| K | ARG178 |
| K | LEU180 |
| L | LEU89 |
| L | TYR109 |
| L | ALA111 |
| L | HIS113 |
| L | LEU115 |
| L | ASN163 |
| L | THR175 |
| L | HOH211 |
| L | HOH220 |
| L | HOH364 |
| L | HOH605 |
| site_id | DC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ACO L 193 |
| Chain | Residue |
| J | TYR109 |
| J | HIS113 |
| J | ASN145 |
| J | ASN163 |
| J | THR175 |
| J | PRO176 |
| J | HOH210 |
| J | HOH669 |
| L | ASN83 |
| L | GLY103 |
| L | PRO104 |
| L | GLY139 |
| L | GLY140 |
| L | ALA157 |
| L | ALA158 |
| L | GLY174 |
| L | ARG178 |
| L | ARG181 |
| L | HOH198 |
| L | HOH304 |
| L | HOH848 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL L 196 |
| Chain | Residue |
| L | GLU42 |
| L | ARG45 |
| L | GLN49 |
| L | VAL62 |
| L | GLN63 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGgnVvInqgVtIGarSvVAanSvVnqdV |
| Chain | Residue | Details |
| A | ILE138-VAL166 |
