3NYU
X-ray crystal structure of the Wbpe (WlbE) aminotransferase from pseudomonas aeruginosa as the PLP internal aldimine adduct with lysine 185
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0009243 | biological_process | O antigen biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0009243 | biological_process | O antigen biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0071555 | biological_process | cell wall organization |
| C | 0000271 | biological_process | polysaccharide biosynthetic process |
| C | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0009243 | biological_process | O antigen biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0071555 | biological_process | cell wall organization |
| D | 0000271 | biological_process | polysaccharide biosynthetic process |
| D | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| D | 0009243 | biological_process | O antigen biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 368 |
| Chain | Residue |
| A | LEU7 |
| A | PRO183 |
| A | LLP185 |
| A | PRO186 |
| A | GLY188 |
| A | ARG252 |
| A | HOH382 |
| A | HOH395 |
| A | HOH531 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 368 |
| Chain | Residue |
| A | HOH383 |
| A | HOH1038 |
| A | HOH1039 |
| B | HOH1035 |
| B | HOH1036 |
| B | HOH1037 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 369 |
| Chain | Residue |
| B | GLY29 |
| B | GLN30 |
| B | TYR31 |
| B | ILE32 |
| B | HOH1213 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 370 |
| Chain | Residue |
| B | LEU7 |
| B | PRO183 |
| B | LLP185 |
| B | PRO186 |
| B | GLY188 |
| B | ARG252 |
| B | HOH405 |
| B | HOH443 |
| B | HOH600 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 371 |
| Chain | Residue |
| B | ALA50 |
| B | CYS171 |
| B | ASN172 |
| B | SER174 |
| B | PHE197 |
| B | THR198 |
| B | ASN199 |
| B | HOH848 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 372 |
| Chain | Residue |
| A | TYR85 |
| A | PHE182 |
| A | LLP185 |
| B | HIS213 |
| B | ASN227 |
| B | ARG229 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 368 |
| Chain | Residue |
| C | HOH409 |
| C | HOH1040 |
| C | HOH1043 |
| C | HOH1044 |
| D | HOH1041 |
| D | HOH1042 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3NUB |
| Chain | Residue | Details |
| A | GLY29 | |
| B | ARG229 | |
| B | HIS308 | |
| B | TYR309 | |
| C | GLY29 | |
| C | TYR31 | |
| C | SER184 | |
| C | ARG229 | |
| C | HIS308 | |
| C | TYR309 | |
| D | GLY29 | |
| A | TYR31 | |
| D | TYR31 | |
| D | SER184 | |
| D | ARG229 | |
| D | HIS308 | |
| D | TYR309 | |
| A | SER184 | |
| A | ARG229 | |
| A | HIS308 | |
| A | TYR309 | |
| B | GLY29 | |
| B | TYR31 | |
| B | SER184 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:20604544 |
| Chain | Residue | Details |
| A | LLP185 | |
| B | LLP185 | |
| C | LLP185 | |
| D | LLP185 |
