Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE KVS A 204 |
| Chain | Residue |
| A | ARG8 |
| A | ARG112 |
| A | ASP129 |
| A | GLY131 |
| A | ALA132 |
| A | ASP133 |
| A | ASP134 |
| A | ILE151 |
| A | GLY152 |
| A | GLY153 |
| A | VAL186 |
| A | ASP25 |
| A | HOH301 |
| A | HOH303 |
| A | HOH333 |
| A | HOH334 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | VAL82 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | LEU114 |
| A | GLU125 |
| A | ALA126 |
| A | VAL186 |
| A | ASN187 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | ARG14 |
| A | GLY16 |
| A | GLY17 |
| A | ARG118 |
| A | HOH323 |
| A | HOH338 |
| A | HOH382 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | LYS45 |
| A | NLE46 |
| A | HOH313 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | THR116 |
| A | ILE117 |
| A | ARG118 |
| A | TRP146 |
| A | GLU169 |
| A | ILE170 |
| A | ABA171 |
| A | GLY172 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
| A | ALA126-ILE137 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
