3NVS
1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE S3P A 427 |
| Chain | Residue |
| A | LYS22 |
| A | ASP314 |
| A | ASN337 |
| A | LYS341 |
| A | GPJ429 |
| A | HOH503 |
| A | HOH725 |
| A | HOH826 |
| A | SER23 |
| A | ARG27 |
| A | THR97 |
| A | SER170 |
| A | SER171 |
| A | GLN172 |
| A | SER198 |
| A | TYR201 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SKM A 428 |
| Chain | Residue |
| A | LYS22 |
| A | SER23 |
| A | ARG27 |
| A | THR97 |
| A | GLN172 |
| A | TYR201 |
| A | ASP314 |
| A | LYS341 |
| A | GPJ429 |
| A | PO4438 |
| A | HOH503 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GPJ A 429 |
| Chain | Residue |
| A | LYS22 |
| A | ASN94 |
| A | GLY96 |
| A | ARG124 |
| A | GLN172 |
| A | ASP314 |
| A | GLU342 |
| A | ARG345 |
| A | HIS386 |
| A | ARG387 |
| A | LYS412 |
| A | S3P427 |
| A | SKM428 |
| A | HOH604 |
| A | HOH826 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 430 |
| Chain | Residue |
| A | GLU123 |
| A | GLN145 |
| A | HOH753 |
| A | HOH871 |
| A | HOH901 |
| A | HOH927 |
| A | HOH1041 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 431 |
| Chain | Residue |
| A | HOH608 |
| A | HOH732 |
| A | HOH733 |
| A | HOH734 |
| A | HOH735 |
| A | HOH1102 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG A 432 |
| Chain | Residue |
| A | HOH524 |
| A | HOH533 |
| A | HOH740 |
| A | HOH741 |
| A | HOH742 |
| A | HOH743 |
| A | HOH744 |
| A | HOH953 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 433 |
| Chain | Residue |
| A | ASP293 |
| A | ARG354 |
| A | VAL360 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 434 |
| Chain | Residue |
| A | ASN17 |
| A | LYS420 |
| A | GLN423 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 435 |
| Chain | Residue |
| A | ALA378 |
| A | ALA379 |
| A | HOH579 |
| A | HOH971 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 436 |
| Chain | Residue |
| A | ARG354 |
| A | GLU362 |
| A | HOH745 |
| A | HOH866 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE A 437 |
| Chain | Residue |
| A | LYS268 |
| A | ASP279 |
| A | TRP290 |
| A | HOH738 |
| A | HOH751 |
| A | HOH861 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 438 |
| Chain | Residue |
| A | SER170 |
| A | SER171 |
| A | VAL197 |
| A | SER198 |
| A | ASN337 |
| A | LYS341 |
| A | SKM428 |
| A | HOH725 |
| A | HOH826 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially hotolyzed) and glyphosate.","authoringGroup":["Center for Structural Genomics of Infectious Diseases (CSGID)"],"authors":["Minasov G.","Light S.H.","Halavaty A.","Shuvalova G.","Papazisi L.","Anderson W.F."]}},{"source":"PDB","id":"3NVS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
