3NVQ

Molecular mechanism of guidance cue recognition

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001649	biological_process	osteoblast differentiation
A	0001755	biological_process	neural crest cell migration
A	0005178	molecular_function	integrin binding
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007229	biological_process	integrin-mediated signaling pathway
A	0007399	biological_process	nervous system development
A	0007411	biological_process	axon guidance
A	0009897	cellular_component	external side of plasma membrane
A	0016020	cellular_component	membrane
A	0030154	biological_process	cell differentiation
A	0030215	molecular_function	semaphorin receptor binding
A	0030335	biological_process	positive regulation of cell migration
A	0031012	cellular_component	extracellular matrix
A	0038191	molecular_function	neuropilin binding
A	0045499	molecular_function	chemorepellent activity
A	0045773	biological_process	positive regulation of axon extension
A	0050727	biological_process	regulation of inflammatory response
A	0050919	biological_process	negative chemotaxis
A	0060907	biological_process	positive regulation of macrophage cytokine production
A	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
A	0071526	biological_process	semaphorin-plexin signaling pathway
A	0090128	biological_process	regulation of synapse maturation
A	0098552	cellular_component	side of membrane
A	0098793	cellular_component	presynapse
A	0098982	cellular_component	GABA-ergic synapse
B	0017154	molecular_function	semaphorin receptor activity
B	0071526	biological_process	semaphorin-plexin signaling pathway
E	0001649	biological_process	osteoblast differentiation
E	0001755	biological_process	neural crest cell migration
E	0005178	molecular_function	integrin binding
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006954	biological_process	inflammatory response
E	0006955	biological_process	immune response
E	0007229	biological_process	integrin-mediated signaling pathway
E	0007399	biological_process	nervous system development
E	0007411	biological_process	axon guidance
E	0009897	cellular_component	external side of plasma membrane
E	0016020	cellular_component	membrane
E	0030154	biological_process	cell differentiation
E	0030215	molecular_function	semaphorin receptor binding
E	0030335	biological_process	positive regulation of cell migration
E	0031012	cellular_component	extracellular matrix
E	0038191	molecular_function	neuropilin binding
E	0045499	molecular_function	chemorepellent activity
E	0045773	biological_process	positive regulation of axon extension
E	0050727	biological_process	regulation of inflammatory response
E	0050919	biological_process	negative chemotaxis
E	0060907	biological_process	positive regulation of macrophage cytokine production
E	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
E	0071526	biological_process	semaphorin-plexin signaling pathway
E	0090128	biological_process	regulation of synapse maturation
E	0098552	cellular_component	side of membrane
E	0098793	cellular_component	presynapse
E	0098982	cellular_component	GABA-ergic synapse
F	0017154	molecular_function	semaphorin receptor activity
F	0071526	biological_process	semaphorin-plexin signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1708
Details	Domain: {"description":"Sema","evidences":[{"source":"PROSITE-ProRule","id":"PRU00352","evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI2
Number of Residues	170
Details	Domain: {"description":"Ig-like C2-type"}

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Region: {"description":"Interaction with integrins"}

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Motif: {"description":"Cell attachment site","evidences":[{"evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Asymmetric dimethylarginine","evidences":[{"source":"UniProtKB","id":"Q9QUR8","evidenceCode":"ECO:0000250"}]}

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Residue

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site_id	SWS_FT_FI6
Number of Residues	22
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20727575","evidenceCode":"ECO:0000269"}]}

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Residue

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10201933","evidenceCode":"ECO:0000305"}]}

Chain

Residue

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