3NV7
Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 158 |
| Chain | Residue |
| A | HIS18 |
| A | ARG91 |
| A | SER128 |
| A | SER129 |
| A | ACY162 |
| A | HOH164 |
| A | HOH212 |
| A | HOH283 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 159 |
| Chain | Residue |
| A | ASP95 |
| A | PHE96 |
| A | GLU97 |
| A | HOH171 |
| A | HOH181 |
| A | HOH184 |
| A | HOH272 |
| A | ARG91 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 160 |
| Chain | Residue |
| A | LYS42 |
| A | ARG133 |
| A | ACY162 |
| A | HOH164 |
| A | HOH170 |
| A | HOH175 |
| A | HOH283 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 161 |
| Chain | Residue |
| A | HIS38 |
| A | SER47 |
| A | LEU48 |
| A | HOH168 |
| A | HOH189 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACY A 162 |
| Chain | Residue |
| A | GLY9 |
| A | THR10 |
| A | PHE11 |
| A | HIS18 |
| A | LYS42 |
| A | SO4158 |
| A | SO4160 |
| A | HOH170 |
| A | HOH228 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00151","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00151","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21527250","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3OTW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00151","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
