3NUG

Crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase from Mesorhizobium loti

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0042820	biological_process	vitamin B6 catabolic process
A	0050235	molecular_function	pyridoxal 4-dehydrogenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0042820	biological_process	vitamin B6 catabolic process
B	0050235	molecular_function	pyridoxal 4-dehydrogenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0042820	biological_process	vitamin B6 catabolic process
C	0050235	molecular_function	pyridoxal 4-dehydrogenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0042820	biological_process	vitamin B6 catabolic process
D	0050235	molecular_function	pyridoxal 4-dehydrogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAD A 251

Chain	Residue
A	GLY14
A	ASN88
A	ALA89
A	SER90
A	ILE139
A	ALA140
A	SER141
A	TYR154
A	LYS158
A	PRO184
A	GLY185
A	GLN17
A	LEU186
A	ILE187
A	SER189
A	GLY191
A	VAL192
A	HOH261
A	HOH273
A	HOH436
A	HOH454
A	HOH608
A	GLY18
A	HOH909
A	ILE19
A	ASP38
A	ILE39
A	ALA60
A	ASP61
A	ILE62

---

site_id	AC2
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NAD B 251

Chain	Residue
B	GLY14
B	ALA16
B	GLN17
B	GLY18
B	ILE19
B	ASP38
B	ILE39
B	ALA60
B	ASP61
B	ILE62
B	ASN88
B	ALA89
B	SER90
B	VAL92
B	ILE139
B	ALA140
B	TYR154
B	LYS158
B	PRO184
B	GLY185
B	LEU186
B	ILE187
B	SER189
B	GLY191
B	VAL192
B	HOH255
B	HOH258
B	HOH266
B	HOH327
B	HOH328
B	HOH503
B	HOH546
B	HOH800

---

site_id	AC3
Number of Residues	31
Details	BINDING SITE FOR RESIDUE NAD C 251

Chain	Residue
C	GLY14
C	GLN17
C	GLY18
C	ILE19
C	ASP38
C	ILE39
C	ALA60
C	ASP61
C	ILE62
C	ASN88
C	ALA89
C	SER90
C	VAL92
C	ILE139
C	ALA140
C	SER141
C	TYR154
C	LYS158
C	PRO184
C	GLY185
C	LEU186
C	ILE187
C	SER189
C	GLY191
C	VAL192
C	HOH252
C	HOH286
C	HOH305
C	HOH313
C	HOH516
C	HOH830

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACY C 1

Chain	Residue
A	GLN215
A	HIS218
C	ARG232
C	HOH320

---

site_id	AC5
Number of Residues	32
Details	BINDING SITE FOR RESIDUE NAD D 251

Chain	Residue
D	GLN17
D	GLY18
D	ILE19
D	ASP38
D	ILE39
D	ALA60
D	ASP61
D	ILE62
D	ASN88
D	ALA89
D	SER90
D	VAL92
D	VAL111
D	ILE139
D	ALA140
D	SER141
D	TYR154
D	LYS158
D	PRO184
D	GLY185
D	LEU186
D	ILE187
D	SER189
D	GLY191
D	VAL192
D	HOH310
D	HOH317
D	HOH384
D	HOH731
D	HOH739
D	HOH740
D	GLY14

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SntffagtpnMaaYVAAKGGViGFTrALA

Chain	Residue	Details
A	SER141-ALA169

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P69167","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10001","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	100
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P69167","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---