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3NSL

Crystal Structure of S100A3 C30A+C68A double mutant expressed in insect cell

Functional Information from GO Data
ChainGOidnamespacecontents
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0046872molecular_functionmetal ion binding
A0046914molecular_functiontransition metal ion binding
A0048306molecular_functioncalcium-dependent protein binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0046872molecular_functionmetal ion binding
B0046914molecular_functiontransition metal ion binding
B0048306molecular_functioncalcium-dependent protein binding
C0005509molecular_functioncalcium ion binding
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0046872molecular_functionmetal ion binding
C0046914molecular_functiontransition metal ion binding
C0048306molecular_functioncalcium-dependent protein binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0046872molecular_functionmetal ion binding
D0046914molecular_functiontransition metal ion binding
D0048306molecular_functioncalcium-dependent protein binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005737cellular_componentcytoplasm
E0005794cellular_componentGolgi apparatus
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0046872molecular_functionmetal ion binding
E0046914molecular_functiontransition metal ion binding
E0048306molecular_functioncalcium-dependent protein binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005794cellular_componentGolgi apparatus
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0046872molecular_functionmetal ion binding
F0046914molecular_functiontransition metal ion binding
F0048306molecular_functioncalcium-dependent protein binding
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL C 102
ChainResidue
AHOH460
BGLN7
BALA10
BHOH128
CALA30
CGLU33
CHOH108
CHOH129
CHOH282

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE GOL D 102
ChainResidue
CHOH301
DGLU6
DGLN7
DALA10
DHOH120
DHOH309
EALA30
EGLU33
EHOH110
EHOH125

Functional Information from PROSITE/UniProt
site_idPS00303
Number of Residues22
DetailsS100_CABP S-100/ICaBP type calcium binding protein signature. FMsvLDtnkDaevDFvEYvrSL
ChainResidueDetails
APHE58-LEU79

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues42
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
ALYS28
FASP63
FASN65
FASP67
FGLU69
FGLU74
CLYS28
CGLU33
CASP63
CASN65
CASP67
AGLU33
CGLU69
CGLU74
BLYS28
BGLU33
BASP63
BASN65
BASP67
BGLU69
BGLU74
ELYS28
AASP63
EGLU33
EASP63
EASN65
EASP67
EGLU69
EGLU74
DLYS28
DGLU33
DASP63
DASN65
AASN65
DASP67
DGLU69
DGLU74
AASP67
AGLU69
AGLU74
FLYS28
FGLU33

site_idSWS_FT_FI2
Number of Residues24
DetailsBINDING:
ChainResidueDetails
ACYS83
CCYS86
CHIS87
CCYS93
BCYS83
BCYS86
BHIS87
BCYS93
ECYS83
ECYS86
EHIS87
ACYS86
ECYS93
DCYS83
DCYS86
DHIS87
DCYS93
AHIS87
ACYS93
FCYS83
FCYS86
FHIS87
FCYS93
CCYS83

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:12470658
ChainResidueDetails
AALA2
FALA2
CALA2
BALA2
EALA2
DALA2

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: Citrulline; by PAD3 => ECO:0000269|PubMed:18083705
ChainResidueDetails
AARG51
FARG51
CARG51
BARG51
EARG51
DARG51

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PDB entries from 2024-11-06

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