Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 957 A 407 |
| Chain | Residue |
| A | ASP38 |
| A | TRP121 |
| A | ILE124 |
| A | ILE132 |
| A | TYR204 |
| A | ILE232 |
| A | ASP234 |
| A | GLY236 |
| A | THR237 |
| A | HOH413 |
| A | GLY40 |
| A | SER41 |
| A | PRO76 |
| A | TYR77 |
| A | THR78 |
| A | GLY80 |
| A | PHE114 |
| A | ILE116 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 957 B 407 |
| Chain | Residue |
| B | LEU36 |
| B | ASP38 |
| B | GLY40 |
| B | SER41 |
| B | PRO76 |
| B | TYR77 |
| B | THR78 |
| B | GLY80 |
| B | PHE114 |
| B | TRP121 |
| B | ILE124 |
| B | TYR204 |
| B | ILE232 |
| B | ASP234 |
| B | GLY236 |
| B | THR237 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 957 C 407 |
| Chain | Residue |
| C | ASP38 |
| C | GLY40 |
| C | SER41 |
| C | PRO76 |
| C | TYR77 |
| C | THR78 |
| C | PHE114 |
| C | ILE116 |
| C | TRP121 |
| C | ILE132 |
| C | TYR204 |
| C | ILE232 |
| C | ASP234 |
| C | GLY236 |
| C | THR237 |
| C | HOH518 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE35-VAL46 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP234 | |
| B | ASP38 | |
| B | ASP234 | |
| C | ASP38 | |
| C | ASP234 | |
| Chain | Residue | Details |
| A | LYS71 | |
| B | LYS224 | |
| B | LYS230 | |
| B | LYS244 | |
| B | LYS245 | |
| B | LYS252 | |
| C | LYS71 | |
| C | LYS220 | |
| C | LYS224 | |
| C | LYS230 | |
| C | LYS244 | |
| A | LYS220 | |
| C | LYS245 | |
| C | LYS252 | |
| A | LYS224 | |
| A | LYS230 | |
| A | LYS244 | |
| A | LYS245 | |
| A | LYS252 | |
| B | LYS71 | |
| B | LYS220 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN98 | |
| C | ASN117 | |
| C | ASN168 | |
| C | ASN299 | |
| A | ASN117 | |
| A | ASN168 | |
| A | ASN299 | |
| B | ASN98 | |
| B | ASN117 | |
| B | ASN168 | |
| B | ASN299 | |
| C | ASN98 | |
