3NRB
Crystal structure of a formyltetrahydrofolate deformylase (purU, PP_1943) from PSEUDOMONAS PUTIDA KT2440 at 2.05 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0008864 | molecular_function | formyltetrahydrofolate deformylase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 287 |
| Chain | Residue |
| A | ARG244 |
| A | ASP249 |
| A | HOH375 |
| A | HOH524 |
| A | HOH564 |
| C | HOH307 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC A 289 |
| Chain | Residue |
| A | LYS204 |
| A | PRO205 |
| A | TYR206 |
| A | HIS207 |
| A | VAL251 |
| A | HOH352 |
| A | HOH487 |
| A | PHE97 |
| A | MSE174 |
| A | HIS194 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 290 |
| Chain | Residue |
| A | PRO83 |
| A | ARG84 |
| A | LEU270 |
| A | ASP272 |
| A | HOH409 |
| A | HOH735 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD A 291 |
| Chain | Residue |
| A | ASN123 |
| A | HIS124 |
| A | MSE174 |
| A | GLN175 |
| A | HOH311 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 287 |
| Chain | Residue |
| B | GLU112 |
| B | HOH348 |
| B | HOH349 |
| D | ARG255 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 288 |
| Chain | Residue |
| B | LYS74 |
| B | GLN155 |
| B | HOH313 |
| B | HOH375 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 289 |
| Chain | Residue |
| B | ARG82 |
| B | PRO83 |
| B | ASP86 |
| B | LYS88 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD B 290 |
| Chain | Residue |
| B | ASN123 |
| B | HIS124 |
| B | MSE174 |
| B | GLN175 |
| B | HOH323 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 287 |
| Chain | Residue |
| C | LYS96 |
| C | ASP98 |
| C | ALA128 |
| C | LEU129 |
| C | HOH322 |
| C | HOH573 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 288 |
| Chain | Residue |
| A | ASN30 |
| C | SER154 |
| C | LYS157 |
| C | HOH402 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD C 289 |
| Chain | Residue |
| C | ASN123 |
| C | HIS124 |
| C | MSE174 |
| C | GLN175 |
| C | HOH358 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 287 |
| Chain | Residue |
| B | HOH451 |
| D | ARG244 |
| D | ASP249 |
| D | HOH371 |
| D | HOH382 |
| D | HOH752 |
| site_id | BC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC D 289 |
| Chain | Residue |
| D | PHE97 |
| D | ARG172 |
| D | HIS194 |
| D | LYS204 |
| D | PRO205 |
| D | TYR206 |
| D | HIS207 |
| D | VAL251 |
| D | HOH332 |
| D | HOH379 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 290 |
| Chain | Residue |
| D | ARG82 |
| D | PRO83 |
| D | LEU270 |
| D | ASP272 |
| D | HOH325 |
| D | HOH358 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 291 |
| Chain | Residue |
| C | HOH382 |
| D | PRO198 |
| D | LYS201 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IMD D 292 |
| Chain | Residue |
| D | ASN123 |
| D | HIS124 |
| D | MSE174 |
| D | GLN175 |
| D | HOH364 |
| D | HOH714 |
