Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 300 |
| Chain | Residue |
| A | ASP184 |
| A | ILE186 |
| A | HOH384 |
| A | HOH530 |
| A | HOH678 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 301 |
| Chain | Residue |
| A | HOH356 |
| A | HOH496 |
| A | ASP97 |
| A | CL328 |
| A | HOH347 |
| A | HOH354 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 302 |
| Chain | Residue |
| A | GLU160 |
| A | GLU196 |
| A | CL323 |
| B | MSE43 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 307 |
| Chain | Residue |
| A | GLU142 |
| A | GLU267 |
| A | HOH489 |
| B | GLU223 |
| B | HOH705 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 321 |
| Chain | Residue |
| A | ILE186 |
| A | LYS235 |
| B | ILE186 |
| B | LYS235 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 323 |
| Chain | Residue |
| A | GLU160 |
| A | GLU196 |
| A | CD302 |
| B | MSE43 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 328 |
| Chain | Residue |
| A | VAL64 |
| A | THR65 |
| A | LEU66 |
| A | ASP97 |
| A | CD301 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 329 |
| Chain | Residue |
| A | TYR72 |
| A | ILE101 |
| A | SER210 |
| A | SER211 |
| A | PHE212 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 332 |
| Chain | Residue |
| A | ASP50 |
| A | ALA51 |
| A | PHE140 |
| A | SER141 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 333 |
| Chain | Residue |
| A | GLN139 |
| A | PHE140 |
| A | THR265 |
| A | ALA266 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 337 |
| Chain | Residue |
| A | GLN241 |
| A | LEU249 |
| A | GLU250 |
| A | HOH477 |
| A | HOH556 |
| A | HOH631 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 303 |
| Chain | Residue |
| A | GLU223 |
| B | GLU142 |
| B | GLU267 |
| B | HOH412 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 304 |
| Chain | Residue |
| A | HOH520 |
| B | ASP184 |
| B | ILE186 |
| B | HOH397 |
| B | HOH674 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 305 |
| Chain | Residue |
| B | ASP97 |
| B | CL325 |
| B | HOH350 |
| B | HOH357 |
| B | HOH362 |
| B | HOH448 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 306 |
| Chain | Residue |
| A | MSE43 |
| B | GLU160 |
| B | GLU196 |
| B | ACT342 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 308 |
| Chain | Residue |
| B | GLU262 |
| C | LYS235 |
| C | GLU260 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 309 |
| Chain | Residue |
| B | GLU198 |
| B | HOH613 |
| C | GLU79 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 318 |
| Chain | Residue |
| B | GLU113 |
| B | HOH627 |
| D | LYS110 |
| D | GLU113 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 319 |
| Chain | Residue |
| A | GLU260 |
| A | HOH429 |
| B | GLU260 |
| B | HOH464 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 320 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 322 |
| Chain | Residue |
| B | SER141 |
| B | THR144 |
| B | HOH683 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 325 |
| Chain | Residue |
| B | VAL64 |
| B | THR65 |
| B | LEU66 |
| B | ASP97 |
| B | CD305 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 330 |
| Chain | Residue |
| B | GLN139 |
| B | PHE140 |
| B | LYS264 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 331 |
| Chain | Residue |
| B | ASP50 |
| B | ALA51 |
| B | PHE140 |
| B | HOH683 |
| B | THR49 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 335 |
| Chain | Residue |
| B | GLN241 |
| B | LEU249 |
| B | GLU250 |
| B | THR254 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 336 |
| Chain | Residue |
| A | LYS181 |
| B | LYS110 |
| B | VAL111 |
| B | ASP179 |
| B | TYR190 |
| B | ARG192 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 341 |
| Chain | Residue |
| B | SER211 |
| B | PHE212 |
| B | HOH696 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 342 |
| Chain | Residue |
| A | MSE43 |
| B | THR158 |
| B | THR159 |
| B | GLU160 |
| B | GLU196 |
| B | CD306 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD C 310 |
| Chain | Residue |
| C | ASP97 |
| C | CL326 |
| C | HOH359 |
| C | HOH392 |
| C | HOH408 |
| C | HOH541 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD C 311 |
| Chain | Residue |
| C | GLU160 |
| C | GLU196 |
| C | ACT343 |
| D | MSE43 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD C 313 |
| Chain | Residue |
| B | HOH707 |
| C | GLU262 |
| C | CL324 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD C 316 |
| Chain | Residue |
| C | GLU142 |
| C | GLU267 |
| C | HOH355 |
| D | GLU223 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 324 |
| Chain | Residue |
| B | LYS232 |
| B | THR265 |
| B | HOH707 |
| C | GLU262 |
| C | LYS264 |
| C | CD313 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 326 |
| Chain | Residue |
| C | VAL64 |
| C | THR65 |
| C | LEU66 |
| C | ASP97 |
| C | PRO98 |
| C | CD310 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 334 |
| Chain | Residue |
| C | ILE101 |
| C | SER210 |
| C | SER211 |
| C | PHE212 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 338 |
| Chain | Residue |
| C | GLN241 |
| C | GLU250 |
| C | THR254 |
| C | GLU256 |
| site_id | EC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 343 |
| Chain | Residue |
| C | THR158 |
| C | THR159 |
| C | GLU160 |
| C | GLU196 |
| C | CD311 |
| C | HOH668 |
| D | MSE43 |
| site_id | EC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD D 312 |
| Chain | Residue |
| C | GLU223 |
| D | GLU142 |
| D | GLU267 |
| D | ACT340 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD D 314 |
| Chain | Residue |
| D | ASP97 |
| D | CL327 |
| D | HOH495 |
| D | HOH514 |
| D | HOH515 |
| site_id | EC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD D 315 |
| Chain | Residue |
| C | MSE43 |
| D | THR159 |
| D | GLU160 |
| D | GLU196 |
| site_id | EC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD D 317 |
| Chain | Residue |
| A | GLU79 |
| D | GLU198 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 327 |
| Chain | Residue |
| D | VAL64 |
| D | THR65 |
| D | LEU66 |
| D | ASP97 |
| D | CD314 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG D 339 |
| Chain | Residue |
| D | GLN241 |
| D | LEU249 |
| D | GLU250 |
| D | THR254 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT D 340 |
| Chain | Residue |
| C | GLU223 |
| D | GLU142 |
| D | ALA266 |
| D | GLU267 |
| D | CD312 |
