3NQ8

Optimization of the in silico designed Kemp eliminase KE70 by computational design and directed evolution R4 8/5A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004139	molecular_function	deoxyribose-phosphate aldolase activity
A	0005737	cellular_component	cytoplasm
A	0009264	biological_process	deoxyribonucleotide catabolic process
A	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 A 268

Chain	Residue
A	ALA112
A	ARG207
A	ALA237
A	SER238
A	GLY239
A	SER240
A	LEU241

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BEN A 301

Chain	Residue
A	SER169
A	THR170
A	VAL203
A	HOH306
A	HIS15
A	PHE47

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 A 302

Chain	Residue
A	ASP220
A	GLU221
A	GLU221
A	LEU222
A	PHE223
A	GLY224

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