Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE BMP A 229 |
Chain | Residue |
A | ASP20 |
A | ARG203 |
A | HOH230 |
A | HOH236 |
A | HOH425 |
A | HOH426 |
A | HOH427 |
A | HOH428 |
A | HOH429 |
B | ASP75 |
B | ILE76 |
A | LYS42 |
B | THR79 |
A | ASP70 |
A | LYS72 |
A | MET126 |
A | SER127 |
A | PRO180 |
A | GLN185 |
A | GLY202 |
site_id | AC2 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE BMP B 229 |
Chain | Residue |
A | ASP75 |
A | ILE76 |
A | THR79 |
B | ASP20 |
B | LYS42 |
B | ASP70 |
B | LYS72 |
B | MET126 |
B | SER127 |
B | PRO180 |
B | VAL182 |
B | GLN185 |
B | GLY202 |
B | ARG203 |
B | HOH246 |
B | HOH251 |
B | HOH432 |
B | HOH433 |
B | HOH434 |
B | HOH435 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL B 230 |
Chain | Residue |
A | ASN210 |
A | HOH262 |
A | HOH264 |
A | HOH302 |
B | THR159 |
B | PRO161 |
B | GLY186 |
B | HOH436 |
Functional Information from PROSITE/UniProt
site_id | PS00156 |
Number of Residues | 14 |
Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDaKvaDIPeTN |
Chain | Residue | Details |
A | ILE67-ASN80 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | LYS72 | |
B | LYS72 | |
site_id | SWS_FT_FI2 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP20 | |
B | ASP70 | |
B | SER127 | |
B | PRO180 | |
B | GLY202 | |
B | ARG203 | |
A | LYS42 | |
A | ASP70 | |
A | SER127 | |
A | PRO180 | |
A | GLY202 | |
A | ARG203 | |
B | ASP20 | |
B | LYS42 | |