Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU A 501 |
| Chain | Residue |
| A | HIS204 |
| A | HIS208 |
| A | PHE227 |
| A | HIS231 |
| A | HOH350 |
| A | CU502 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CU A 502 |
| Chain | Residue |
| A | HOH347 |
| A | HOH348 |
| A | HOH350 |
| A | CU501 |
| A | HIS42 |
| A | HIS60 |
| A | HIS69 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 505 |
| Chain | Residue |
| A | HIS13 |
| A | ASP287 |
| A | CL510 |
| A | CL511 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 506 |
| Chain | Residue |
| A | HIS49 |
| A | CL513 |
| B | GLN142 |
| B | ASN144 |
| B | CL512 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 507 |
| Chain | Residue |
| A | GLU95 |
| A | ARG165 |
| A | HOH357 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 508 |
| Chain | Residue |
| A | ASP166 |
| A | HOH384 |
| B | ASP123 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 509 |
| Chain | Residue |
| A | HIS279 |
| A | HOH385 |
| A | HOH386 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 510 |
| Chain | Residue |
| A | HIS13 |
| A | ASP287 |
| A | ZN505 |
| A | CL511 |
| B | MET100 |
| B | GLN101 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 511 |
| Chain | Residue |
| A | LYS9 |
| A | HIS13 |
| A | ZN505 |
| A | CL510 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 513 |
| Chain | Residue |
| A | HIS49 |
| A | ZN506 |
| B | CL512 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 512 |
| Chain | Residue |
| A | HIS49 |
| A | ZN506 |
| A | CL513 |
| B | ASN144 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU B 501 |
| Chain | Residue |
| B | HIS204 |
| B | HIS208 |
| B | PHE227 |
| B | HIS231 |
| B | HOH342 |
| B | CU502 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU B 502 |
| Chain | Residue |
| B | HIS42 |
| B | HIS60 |
| B | HIS69 |
| B | HOH342 |
| B | HOH343 |
| B | CU501 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 505 |
| Chain | Residue |
| B | HIS13 |
| B | ASP287 |
| B | CL508 |
| B | CL509 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 506 |
| Chain | Residue |
| A | GLN142 |
| A | ASN144 |
| B | HIS49 |
| B | HOH376 |
| B | HOH388 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 507 |
| Chain | Residue |
| B | ILE243 |
| B | HIS279 |
| B | HOH377 |
| B | HOH378 |
| B | HOH380 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 508 |
| Chain | Residue |
| B | LYS9 |
| B | HIS13 |
| B | ASP287 |
| B | ZN505 |
| B | CL509 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 509 |
| Chain | Residue |
| A | MET100 |
| A | GLN101 |
| B | HIS13 |
| B | ASP287 |
| B | ILE288 |
| B | ZN505 |
| B | CL508 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hmssa.FLpWHReyLlrfE |
| Chain | Residue | Details |
| A | HIS60-GLU77 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFFlhHanvD |
| Chain | Residue | Details |
| A | ASP224-ASP235 | |
