3NMU

Crystal Structure of substrate-bound halfmer box C/D RNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0030515	molecular_function	snoRNA binding
A	0031428	cellular_component	box C/D methylation guide snoRNP complex
A	0032040	cellular_component	small-subunit processome
B	0005515	molecular_function	protein binding
B	0030515	molecular_function	snoRNA binding
B	0031428	cellular_component	box C/D methylation guide snoRNP complex
B	0032040	cellular_component	small-subunit processome
C	0001682	biological_process	tRNA 5'-leader removal
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0004526	molecular_function	ribonuclease P activity
C	0005737	cellular_component	cytoplasm
C	0005840	cellular_component	ribosome
C	0006364	biological_process	rRNA processing
C	0006412	biological_process	translation
C	0008033	biological_process	tRNA processing
C	0019843	molecular_function	rRNA binding
C	0042254	biological_process	ribosome biogenesis
C	1990904	cellular_component	ribonucleoprotein complex
F	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0006338	biological_process	chromatin remodeling
F	0006364	biological_process	rRNA processing
F	0008033	biological_process	tRNA processing
F	0008168	molecular_function	methyltransferase activity
F	0008649	molecular_function	rRNA methyltransferase activity
F	0016740	molecular_function	transferase activity
F	0031167	biological_process	rRNA methylation
F	0032259	biological_process	methylation
F	1990259	molecular_function	histone H2AQ104 methyltransferase activity
G	0001682	biological_process	tRNA 5'-leader removal
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0004526	molecular_function	ribonuclease P activity
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006364	biological_process	rRNA processing
G	0006412	biological_process	translation
G	0008033	biological_process	tRNA processing
G	0019843	molecular_function	rRNA binding
G	0042254	biological_process	ribosome biogenesis
G	1990904	cellular_component	ribonucleoprotein complex
J	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0006338	biological_process	chromatin remodeling
J	0006364	biological_process	rRNA processing
J	0008033	biological_process	tRNA processing
J	0008168	molecular_function	methyltransferase activity
J	0008649	molecular_function	rRNA methyltransferase activity
J	0016740	molecular_function	transferase activity
J	0031167	biological_process	rRNA methylation
J	0032259	biological_process	methylation
J	1990259	molecular_function	histone H2AQ104 methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SAM F 228

Chain	Residue
A	GLU352
F	ASP150
F	GLN153
A	TYR353
F	LYS57
F	GLY81
F	ALA83
F	GLU105
F	PHE106
F	ASP130
F	ALA131

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SAM J 228

Chain	Residue
B	GLU352
B	TYR353
J	LYS57
J	GLY81
J	ALA83
J	GLU105
J	PHE106
J	ALA131
J	ASP150
J	GLN153
J	HOH230

---

Functional Information from PROSITE/UniProt

site_id	PS00566
Number of Residues	15
Details	FIBRILLARIN Fibrillarin signature. GKIYGIEFSpRvlRE

Chain	Residue	Details
F	GLY99-GLU113

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CeekeIPYiyVpSKkeLG

Chain	Residue	Details
C	CYS71-GLY88

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00351","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {}

Chain

Residue

Details

---