3NJ0
X-ray crystal structure of the PYL2-pyrabactin A complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| A | 0010427 | molecular_function | abscisic acid binding |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0062049 | cellular_component | protein phosphatase inhibitor complex |
| B | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| B | 0010427 | molecular_function | abscisic acid binding |
| B | 0038023 | molecular_function | signaling receptor activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0062049 | cellular_component | protein phosphatase inhibitor complex |
| C | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| C | 0010427 | molecular_function | abscisic acid binding |
| C | 0038023 | molecular_function | signaling receptor activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0062049 | cellular_component | protein phosphatase inhibitor complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PYV A 300 |
| Chain | Residue |
| A | LYS64 |
| A | PEG191 |
| A | HOH214 |
| A | HOH284 |
| A | HOH285 |
| A | GLU98 |
| A | PHE112 |
| A | VAL114 |
| A | LEU121 |
| A | TYR124 |
| A | PHE165 |
| A | VAL169 |
| A | ASN173 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 191 |
| Chain | Residue |
| A | PHE66 |
| A | PYV300 |
| B | SER89 |
| B | PHE165 |
| B | PYV300 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PYV B 300 |
| Chain | Residue |
| A | PEG191 |
| B | LYS64 |
| B | VAL87 |
| B | GLU98 |
| B | PHE112 |
| B | VAL114 |
| B | LEU121 |
| B | TYR124 |
| B | PHE165 |
| B | VAL169 |
| B | ASN173 |
| B | HOH209 |
| B | HOH229 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PYV C 300 |
| Chain | Residue |
| C | LYS64 |
| C | VAL87 |
| C | GLU98 |
| C | PHE112 |
| C | VAL114 |
| C | LEU121 |
| C | TYR124 |
| C | PHE165 |
| C | VAL166 |
| C | VAL169 |
| C | PEG191 |
| C | GOL192 |
| C | HOH278 |
| C | HOH279 |
| C | HOH291 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG C 191 |
| Chain | Residue |
| C | PHE66 |
| C | PHE165 |
| C | PHE165 |
| C | GOL192 |
| C | PYV300 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 192 |
| Chain | Residue |
| C | GLY90 |
| C | HIS119 |
| C | ARG120 |
| C | LEU121 |
| C | PEG191 |
| C | PYV300 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Motif: {"description":"Gate loop","evidences":[{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Motif: {"description":"Latch loop","evidences":[{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 39 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19893533","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"Involved in interactions with PP2Cs","evidences":[{"source":"UniProtKB","id":"O49686","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Site: {"description":"Involved in ABA binding","evidences":[{"source":"UniProtKB","id":"Q84MC7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
