3NIL
The structure of UBR box (RDAA)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| A | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0061630 | molecular_function | ubiquitin protein ligase activity |
| B | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0061630 | molecular_function | ubiquitin protein ligase activity |
| D | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
| F | 0008270 | molecular_function | zinc ion binding |
| F | 0061630 | molecular_function | ubiquitin protein ligase activity |
| F | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | CYS123 |
| A | CYS148 |
| A | CYS151 |
| A | CYS175 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2 |
| Chain | Residue |
| A | HIS118 |
| A | CYS151 |
| A | CYS177 |
| A | CYS189 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 3 |
| Chain | Residue |
| A | CYS139 |
| A | HIS157 |
| A | HIS160 |
| A | CYS136 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1 |
| Chain | Residue |
| B | CYS123 |
| B | CYS148 |
| B | CYS151 |
| B | CYS175 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | HIS118 |
| B | CYS151 |
| B | CYS177 |
| B | CYS189 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 3 |
| Chain | Residue |
| B | CYS136 |
| B | CYS139 |
| B | HIS157 |
| B | HIS160 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1 |
| Chain | Residue |
| D | CYS123 |
| D | CYS148 |
| D | CYS151 |
| D | CYS175 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 2 |
| Chain | Residue |
| D | HIS118 |
| D | CYS151 |
| D | CYS177 |
| D | CYS189 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 3 |
| Chain | Residue |
| D | CYS136 |
| D | CYS139 |
| D | HIS157 |
| D | HIS160 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 1 |
| Chain | Residue |
| F | CYS123 |
| F | CYS148 |
| F | CYS151 |
| F | CYS175 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 2 |
| Chain | Residue |
| F | HIS118 |
| F | CYS151 |
| F | CYS177 |
| F | CYS189 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN F 3 |
| Chain | Residue |
| F | CYS136 |
| F | CYS139 |
| F | ASP156 |
| F | HIS157 |
| F | HIS160 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT F 195 |
| Chain | Residue |
| F | THR164 |
| F | HOH407 |
| F | HOH443 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT F 196 |
| Chain | Residue |
| F | GLU181 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 292 |
| Details | ZN_FING: UBR-type => ECO:0000255|PROSITE-ProRule:PRU00508 |
| Chain | Residue | Details |
| A | ARG121-GLN194 | |
| B | ARG121-GLN194 | |
| D | ARG121-GLN194 | |
| F | ARG121-GLN194 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:34789879, ECO:0007744|PDB:7MEX, ECO:0007744|PDB:7MEY |
| Chain | Residue | Details |
| A | HIS118 | |
| A | CYS175 | |
| A | CYS177 | |
| A | CYS189 | |
| B | HIS118 | |
| B | CYS123 | |
| B | CYS136 | |
| B | CYS139 | |
| B | CYS148 | |
| B | CYS151 | |
| B | HIS157 | |
| A | CYS123 | |
| B | HIS160 | |
| B | HIS161 | |
| B | CYS175 | |
| B | CYS177 | |
| B | CYS189 | |
| D | HIS118 | |
| D | CYS123 | |
| D | CYS136 | |
| D | CYS139 | |
| D | CYS148 | |
| A | CYS136 | |
| D | CYS151 | |
| D | HIS157 | |
| D | HIS160 | |
| D | HIS161 | |
| D | CYS175 | |
| D | CYS177 | |
| D | CYS189 | |
| F | HIS118 | |
| F | CYS123 | |
| F | CYS136 | |
| A | CYS139 | |
| F | CYS139 | |
| F | CYS148 | |
| F | CYS151 | |
| F | HIS157 | |
| F | HIS160 | |
| F | HIS161 | |
| F | CYS175 | |
| F | CYS177 | |
| F | CYS189 | |
| A | CYS148 | |
| A | CYS151 | |
| A | HIS157 | |
| A | HIS160 | |
| A | HIS161 |
