3NHO
Complex of 6-hydroxy-L-nicotine oxidase with product bound at active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0000166 | molecular_function | nucleotide binding |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0009820 | biological_process | alkaloid metabolic process |
| X | 0016491 | molecular_function | oxidoreductase activity |
| X | 0018531 | molecular_function | (S)-6-hydroxynicotine oxidase activity |
| X | 0019608 | biological_process | nicotine catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HNM X 433 |
| Chain | Residue |
| X | ASN166 |
| X | HOH538 |
| X | HOH586 |
| X | MET167 |
| X | TRP179 |
| X | LEU183 |
| X | PHE326 |
| X | TRP371 |
| X | VAL372 |
| X | PRO405 |
| X | FAD434 |
| site_id | AC2 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD X 434 |
| Chain | Residue |
| X | VAL7 |
| X | GLY8 |
| X | GLY9 |
| X | GLY10 |
| X | PHE11 |
| X | SER12 |
| X | LEU30 |
| X | GLU31 |
| X | GLY32 |
| X | GLY37 |
| X | GLY38 |
| X | ARG39 |
| X | GLY56 |
| X | GLY57 |
| X | ALA58 |
| X | TYR59 |
| X | THR224 |
| X | VAL226 |
| X | ALA254 |
| X | THR255 |
| X | PRO256 |
| X | LEU366 |
| X | PHE367 |
| X | PRO370 |
| X | TRP371 |
| X | GLY397 |
| X | SER398 |
| X | GLY406 |
| X | TYR407 |
| X | ILE408 |
| X | HNM433 |
| X | HOH469 |
| X | HOH476 |
| X | HOH505 |
| X | HOH674 |
| X | HOH746 |
| X | HOH1035 |
| X | HOH1042 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GP7 X 435 |
| Chain | Residue |
| X | GLN99 |
| X | PRO104 |
| X | GLY105 |
| X | ALA108 |
| X | THR115 |
| X | PHE159 |
| X | MET180 |
| X | VAL194 |
| X | HOH588 |
| X | HOH698 |
| X | HOH733 |
| X | HOH1019 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20006620, ECO:0000269|PubMed:21383134, ECO:0007744|PDB:3K7M, ECO:0007744|PDB:3K7Q, ECO:0007744|PDB:3K7T, ECO:0007744|PDB:3NG7, ECO:0007744|PDB:3NGC, ECO:0007744|PDB:3NH3, ECO:0007744|PDB:3NHO, ECO:0007744|PDB:3NK0, ECO:0007744|PDB:3NK1, ECO:0007744|PDB:3NK2, ECO:0007744|PDB:3NN0 |
| Chain | Residue | Details |
| X | SER12 | |
| X | GLU31 | |
| X | GLY38 | |
| X | GLY56 | |
| X | VAL226 | |
| X | SER398 | |
| X | GLY406 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20006620, ECO:0000269|PubMed:21383134, ECO:0007744|PDB:3K7Q, ECO:0007744|PDB:3NG7, ECO:0007744|PDB:3NGC, ECO:0007744|PDB:3NH3 |
| Chain | Residue | Details |
| X | ASN166 | |
| X | TYR311 | |
| X | PHE326 | |
| X | TYR407 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20006620, ECO:0000269|PubMed:21383134, ECO:0007744|PDB:3NG7, ECO:0007744|PDB:3NGC, ECO:0007744|PDB:3NH3 |
| Chain | Residue | Details |
| X | TRP371 |
