3NGX

Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004477	molecular_function	methenyltetrahydrofolate cyclohydrolase activity
A	0004488	molecular_function	methylenetetrahydrofolate dehydrogenase (NADP+) activity
A	0005829	cellular_component	cytosol
A	0035999	biological_process	tetrahydrofolate interconversion
B	0003824	molecular_function	catalytic activity
B	0004477	molecular_function	methenyltetrahydrofolate cyclohydrolase activity
B	0004488	molecular_function	methylenetetrahydrofolate dehydrogenase (NADP+) activity
B	0005829	cellular_component	cytosol
B	0035999	biological_process	tetrahydrofolate interconversion

Functional Information from PROSITE/UniProt

site_id	PS00767
Number of Residues	9
Details	THF_DHG_CYH_2 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. PGGVGPITA

Chain	Residue	Details
A	PRO250-ALA258

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01576","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21333632","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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