3NGN
Crystal structure of the human CNOT6L nuclease domain in complex with AMP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE AMP A 556 |
| Chain | Residue |
| A | GLU240 |
| A | HIS529 |
| A | HOH592 |
| A | HOH614 |
| A | HIS360 |
| A | TRP363 |
| A | PRO365 |
| A | LYS371 |
| A | ASP410 |
| A | ASN412 |
| A | ASN479 |
| A | PHE484 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AMP A 557 |
| Chain | Residue |
| A | TRP174 |
| A | SER188 |
| A | THR190 |
| A | ILE271 |
| A | MET272 |
| A | SER273 |
| A | GLU276 |
| A | GLN535 |
| A | HOH558 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27013054","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27013054","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DV2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NGN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NGQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20628353","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27013054","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DV2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
