3NG3

Crystal structure of deoxyribose phosphate aldolase from mycobacterium avium 104 in a schiff base with an unknown aldehyde

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004139	molecular_function	deoxyribose-phosphate aldolase activity
A	0005737	cellular_component	cytoplasm
A	0009264	biological_process	deoxyribonucleotide catabolic process
A	0016052	biological_process	carbohydrate catabolic process
A	0016829	molecular_function	lyase activity
A	0046386	biological_process	deoxyribose phosphate catabolic process
B	0003824	molecular_function	catalytic activity
B	0004139	molecular_function	deoxyribose-phosphate aldolase activity
B	0005737	cellular_component	cytoplasm
B	0009264	biological_process	deoxyribonucleotide catabolic process
B	0016052	biological_process	carbohydrate catabolic process
B	0016829	molecular_function	lyase activity
B	0046386	biological_process	deoxyribose phosphate catabolic process
C	0003824	molecular_function	catalytic activity
C	0004139	molecular_function	deoxyribose-phosphate aldolase activity
C	0005737	cellular_component	cytoplasm
C	0009264	biological_process	deoxyribonucleotide catabolic process
C	0016052	biological_process	carbohydrate catabolic process
C	0016829	molecular_function	lyase activity
C	0046386	biological_process	deoxyribose phosphate catabolic process
D	0003824	molecular_function	catalytic activity
D	0004139	molecular_function	deoxyribose-phosphate aldolase activity
D	0005737	cellular_component	cytoplasm
D	0009264	biological_process	deoxyribonucleotide catabolic process
D	0016052	biological_process	carbohydrate catabolic process
D	0016829	molecular_function	lyase activity
D	0046386	biological_process	deoxyribose phosphate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 224

Chain	Residue
A	THR195
D	SER131
D	SER170

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 224

Chain	Residue
B	HOH274
B	HIS71
B	VAL72
B	SER73
B	LYS76
B	ASP96
B	ASP111

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 224

Chain	Residue
C	VAL30
C	VAL58
C	ARG59

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 225

Chain	Residue
B	ARG147
B	GLU179
C	ASP106
C	ARG109

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO D 224

Chain	Residue
C	ALA21
C	THR22
C	ALA23
D	GLY98
D	ALA99
D	ALA102
D	HOH286
D	HOH478

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00114

Chain	Residue	Details
A	ASP92
A	LYS188
B	ASP92
B	LYS188
C	ASP92
C	LYS188
D	ASP92
D	LYS188

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with acetaldehyde => ECO:0000255|HAMAP-Rule:MF_00114

Chain	Residue	Details
A	LYS158
B	LYS158
C	LYS158
D	LYS158

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