3NFC

Crystal structure of E.coli MazF Toxin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006402	biological_process	mRNA catabolic process
A	0006417	biological_process	regulation of translation
A	0009372	biological_process	quorum sensing
A	0016075	biological_process	rRNA catabolic process
A	0030308	biological_process	negative regulation of cell growth
A	0032991	cellular_component	protein-containing complex
A	0040008	biological_process	regulation of growth
A	0042803	molecular_function	protein homodimerization activity
A	0043068	biological_process	positive regulation of programmed cell death
A	0044010	biological_process	single-species biofilm formation
A	0044877	molecular_function	protein-containing complex binding
A	0051607	biological_process	defense response to virus
A	0110001	cellular_component	toxin-antitoxin complex
A	0140677	molecular_function	molecular function activator activity
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0004519	molecular_function	endonuclease activity
B	0004521	molecular_function	RNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006402	biological_process	mRNA catabolic process
B	0006417	biological_process	regulation of translation
B	0009372	biological_process	quorum sensing
B	0016075	biological_process	rRNA catabolic process
B	0030308	biological_process	negative regulation of cell growth
B	0032991	cellular_component	protein-containing complex
B	0040008	biological_process	regulation of growth
B	0042803	molecular_function	protein homodimerization activity
B	0043068	biological_process	positive regulation of programmed cell death
B	0044010	biological_process	single-species biofilm formation
B	0044877	molecular_function	protein-containing complex binding
B	0051607	biological_process	defense response to virus
B	0110001	cellular_component	toxin-antitoxin complex
B	0140677	molecular_function	molecular function activator activity
C	0003677	molecular_function	DNA binding
C	0003723	molecular_function	RNA binding
C	0004519	molecular_function	endonuclease activity
C	0004521	molecular_function	RNA endonuclease activity
C	0005515	molecular_function	protein binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006402	biological_process	mRNA catabolic process
C	0006417	biological_process	regulation of translation
C	0009372	biological_process	quorum sensing
C	0016075	biological_process	rRNA catabolic process
C	0030308	biological_process	negative regulation of cell growth
C	0032991	cellular_component	protein-containing complex
C	0040008	biological_process	regulation of growth
C	0042803	molecular_function	protein homodimerization activity
C	0043068	biological_process	positive regulation of programmed cell death
C	0044010	biological_process	single-species biofilm formation
C	0044877	molecular_function	protein-containing complex binding
C	0051607	biological_process	defense response to virus
C	0110001	cellular_component	toxin-antitoxin complex
C	0140677	molecular_function	molecular function activator activity
D	0003677	molecular_function	DNA binding
D	0003723	molecular_function	RNA binding
D	0004519	molecular_function	endonuclease activity
D	0004521	molecular_function	RNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006402	biological_process	mRNA catabolic process
D	0006417	biological_process	regulation of translation
D	0009372	biological_process	quorum sensing
D	0016075	biological_process	rRNA catabolic process
D	0030308	biological_process	negative regulation of cell growth
D	0032991	cellular_component	protein-containing complex
D	0040008	biological_process	regulation of growth
D	0042803	molecular_function	protein homodimerization activity
D	0043068	biological_process	positive regulation of programmed cell death
D	0044010	biological_process	single-species biofilm formation
D	0044877	molecular_function	protein-containing complex binding
D	0051607	biological_process	defense response to virus
D	0110001	cellular_component	toxin-antitoxin complex
D	0140677	molecular_function	molecular function activator activity
E	0003677	molecular_function	DNA binding
E	0003723	molecular_function	RNA binding
E	0004519	molecular_function	endonuclease activity
E	0004521	molecular_function	RNA endonuclease activity
E	0005515	molecular_function	protein binding
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006402	biological_process	mRNA catabolic process
E	0006417	biological_process	regulation of translation
E	0009372	biological_process	quorum sensing
E	0016075	biological_process	rRNA catabolic process
E	0030308	biological_process	negative regulation of cell growth
E	0032991	cellular_component	protein-containing complex
E	0040008	biological_process	regulation of growth
E	0042803	molecular_function	protein homodimerization activity
E	0043068	biological_process	positive regulation of programmed cell death
E	0044010	biological_process	single-species biofilm formation
E	0044877	molecular_function	protein-containing complex binding
E	0051607	biological_process	defense response to virus
E	0110001	cellular_component	toxin-antitoxin complex
E	0140677	molecular_function	molecular function activator activity
F	0003677	molecular_function	DNA binding
F	0003723	molecular_function	RNA binding
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0005515	molecular_function	protein binding
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006402	biological_process	mRNA catabolic process
F	0006417	biological_process	regulation of translation
F	0009372	biological_process	quorum sensing
F	0016075	biological_process	rRNA catabolic process
F	0030308	biological_process	negative regulation of cell growth
F	0032991	cellular_component	protein-containing complex
F	0040008	biological_process	regulation of growth
F	0042803	molecular_function	protein homodimerization activity
F	0043068	biological_process	positive regulation of programmed cell death
F	0044010	biological_process	single-species biofilm formation
F	0044877	molecular_function	protein-containing complex binding
F	0051607	biological_process	defense response to virus
F	0110001	cellular_component	toxin-antitoxin complex
F	0140677	molecular_function	molecular function activator activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: ADP-ribosylarginine => ECO:0000269|PubMed:26395283

Chain	Residue	Details
A	ARG4
B	ARG4
C	ARG4
D	ARG4
E	ARG4
F	ARG4

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