3NEM
Aspartyl-tRNA synthetase complexed with aspartyl adenylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| A | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| B | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE AMO A 439 |
| Chain | Residue |
| A | GLU170 |
| A | ILE362 |
| A | SER363 |
| A | SER364 |
| A | GLY365 |
| A | ARG368 |
| A | PHE406 |
| A | GLY407 |
| A | GLY409 |
| A | ARG412 |
| A | HOH2046 |
| A | GLN192 |
| A | HOH2063 |
| A | HOH2124 |
| A | LYS195 |
| A | ARG214 |
| A | GLU216 |
| A | HIS223 |
| A | LEU224 |
| A | TYR339 |
| A | GLU361 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ATP B 1039 |
| Chain | Residue |
| B | ARG214 |
| B | GLU216 |
| B | HIS223 |
| B | LEU224 |
| B | ALA227 |
| B | GLU361 |
| B | ILE362 |
| B | SER363 |
| B | SER364 |
| B | GLY407 |
| B | GLY409 |
| B | ARG412 |
| B | MG1040 |
| B | MG1041 |
| B | MG1042 |
| B | HOH2029 |
| B | HOH2249 |
| B | HOH2250 |
| B | HOH2251 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1040 |
| Chain | Residue |
| B | ATP1039 |
| B | HOH2248 |
| B | HOH2249 |
| B | HOH2250 |
| B | HOH2251 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1041 |
| Chain | Residue |
| B | GLU361 |
| B | ATP1039 |
| B | MG1042 |
| B | HOH2252 |
| B | HOH2253 |
| B | HOH2340 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1042 |
| Chain | Residue |
| B | GLU361 |
| B | SER364 |
| B | ATP1039 |
| B | MG1041 |
| B | HOH2253 |
| B | HOH2311 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU170 | |
| B | ARG222 | |
| B | GLU361 | |
| B | SER364 | |
| B | ARG368 | |
| B | GLY409 | |
| A | ARG214 | |
| A | ARG222 | |
| A | GLU361 | |
| A | SER364 | |
| A | ARG368 | |
| A | GLY409 | |
| B | GLU170 | |
| B | ARG214 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for tRNA discrimination |
| Chain | Residue | Details |
| A | TRP26 | |
| A | LYS85 | |
| B | TRP26 | |
| B | LYS85 |
