Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 29 |
Details | BINDING SITE FOR RESIDUE ROC A 101 |
Chain | Residue |
A | ARG9 |
A | GLY50 |
A | ILE51 |
A | THR81 |
A | PRO82 |
A | ILE85 |
A | HOH116 |
A | HOH324 |
B | ARG9 |
B | ASP26 |
B | GLY28 |
A | ASP26 |
B | ALA29 |
B | ASP30 |
B | ASP31 |
B | GLY49 |
B | GLY50 |
B | ILE51 |
B | PRO82 |
B | ILE85 |
B | HOH119 |
C | TRP6 |
A | GLY28 |
A | ALA29 |
A | ASP30 |
A | ASP31 |
A | VAL33 |
A | ILE48 |
A | GLY49 |
site_id | AC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL A 102 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE DMS A 103 |
Chain | Residue |
A | LYS15 |
A | GLY18 |
A | ILE64 |
A | DMS104 |
B | GLY18 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE DMS A 104 |
Chain | Residue |
A | GLY18 |
A | DMS103 |
A | HOH115 |
B | LYS15 |
B | ILE16 |
B | GLY17 |
B | GLY18 |
B | ILE64 |
site_id | AC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL B 102 |
site_id | AC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 103 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE NA C 100 |
Chain | Residue |
C | THR12 |
C | GLU65 |
C | GLY68 |
site_id | AC8 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL C 101 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE DMS C 102 |
Chain | Residue |
C | GLY17 |
C | DMS103 |
D | LYS14 |
D | ILE15 |
D | GLY16 |
D | GLY17 |
D | ILE63 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE DMS C 103 |
Chain | Residue |
C | LYS14 |
C | ILE15 |
C | GLY16 |
C | GLY17 |
C | DMS102 |
D | GLY17 |
site_id | BC2 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE ROC D 100 |
Chain | Residue |
C | ARG8 |
C | LEU23 |
C | ASP25 |
C | GLY27 |
C | ALA28 |
C | ASP29 |
C | ASP30 |
C | GLY48 |
C | GLY49 |
C | ILE50 |
C | PRO81 |
C | ILE84 |
C | HOH107 |
D | ARG8 |
D | ASP25 |
D | GLY27 |
D | ALA28 |
D | ASP29 |
D | ASP30 |
D | GLY48 |
D | GLY49 |
D | ILE50 |
D | THR80 |
D | ILE84 |
D | HOH102 |
D | HOH116 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA23-ILE34 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | LIPID: N-myristoyl glycine; by host => ECO:0000250 |
Chain | Residue | Details |
A | GLN3 | |
B | GLN3 | |
C | GLN2 | |
D | GLN2 | |