3ND5

Crystal structure of phosphopantetheine adenylyltransferase (PPAT) from Enterococcus faecalis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0015937	biological_process	coenzyme A biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0009058	biological_process	biosynthetic process
B	0015937	biological_process	coenzyme A biosynthetic process
B	0016779	molecular_function	nucleotidyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0009058	biological_process	biosynthetic process
C	0015937	biological_process	coenzyme A biosynthetic process
C	0016779	molecular_function	nucleotidyltransferase activity
D	0003824	molecular_function	catalytic activity
D	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0009058	biological_process	biosynthetic process
D	0015937	biological_process	coenzyme A biosynthetic process
D	0016779	molecular_function	nucleotidyltransferase activity
E	0003824	molecular_function	catalytic activity
E	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0009058	biological_process	biosynthetic process
E	0015937	biological_process	coenzyme A biosynthetic process
E	0016779	molecular_function	nucleotidyltransferase activity
F	0003824	molecular_function	catalytic activity
F	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0009058	biological_process	biosynthetic process
F	0015937	biological_process	coenzyme A biosynthetic process
F	0016779	molecular_function	nucleotidyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151

Chain	Residue	Details
A	SER10
D	SER10
D	LYS42
D	ARG89
E	SER10
E	LYS42
E	ARG89
F	SER10
F	LYS42
F	ARG89
A	LYS42
A	ARG89
B	SER10
B	LYS42
B	ARG89
C	SER10
C	LYS42
C	ARG89

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site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6

Chain	Residue	Details
A	HIS18
C	GLY90
C	GLU100
C	TYR125
D	HIS18
D	GLY90
D	GLU100
D	TYR125
E	HIS18
E	GLY90
E	GLU100
A	GLY90
E	TYR125
F	HIS18
F	GLY90
F	GLU100
F	TYR125
A	GLU100
A	TYR125
B	HIS18
B	GLY90
B	GLU100
B	TYR125
C	HIS18

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7

Chain	Residue	Details
A	THR75
B	THR75
C	THR75
D	THR75
E	THR75
F	THR75

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site_id	SWS_FT_FI4
Number of Residues	6
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151

Chain	Residue	Details
A	HIS18
B	HIS18
C	HIS18
D	HIS18
E	HIS18
F	HIS18

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