Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 283 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 284 |
| Chain | Residue |
| A | LYS48 |
| A | VAL49 |
| A | HIS115 |
| A | HOH333 |
| A | HOH391 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 285 |
| Chain | Residue |
| A | HIS144 |
| A | PRO145 |
| A | ASP146 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 283 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 284 |
| Chain | Residue |
| B | LYS48 |
| B | VAL49 |
| B | HIS115 |
| B | HOH318 |
| B | HOH341 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 285 |
| Chain | Residue |
| B | HIS144 |
| B | PRO145 |
| B | ASP146 |
| B | LYS265 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 283 |
| Chain | Residue |
| C | LYS48 |
| C | VAL49 |
| C | HIS115 |
| C | HOH357 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 284 |
| Chain | Residue |
| C | HIS144 |
| C | ASP146 |
| C | LYS265 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 285 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 283 |
| Chain | Residue |
| D | HIS180 |
| D | HOH302 |
| G | HIS180 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 284 |
| Chain | Residue |
| D | LYS48 |
| D | VAL49 |
| D | HIS115 |
| D | HOH322 |
| D | HOH341 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 285 |
| Chain | Residue |
| D | HIS144 |
| D | PRO145 |
| D | ASP146 |
| D | LYS265 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL E 283 |
| Chain | Residue |
| E | LYS48 |
| E | VAL49 |
| E | HIS115 |
| E | HOH304 |
| E | HOH342 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 284 |
| Chain | Residue |
| E | HIS144 |
| E | ASP146 |
| E | LYS265 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL G 283 |
| Chain | Residue |
| D | HIS180 |
| G | ALA179 |
| G | HIS180 |
| G | HOH578 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL G 284 |
| Chain | Residue |
| G | LYS48 |
| G | VAL49 |
| G | HIS115 |
| G | HOH2477 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL G 285 |
| Chain | Residue |
| G | HIS144 |
| G | ASP146 |
| G | HOH5358 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL H 283 |
| Chain | Residue |
| H | HIS180 |
| H | HOH4664 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL H 284 |
| Chain | Residue |
| H | LYS48 |
| H | VAL49 |
| H | HIS115 |
| H | HOH406 |
| H | HOH2732 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL H 285 |
| Chain | Residue |
| H | HIS144 |
| H | PRO145 |
| H | ASP146 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL I 283 |
| Chain | Residue |
| I | LYS48 |
| I | VAL49 |
| I | HIS115 |
| I | HOH410 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL I 284 |
| Chain | Residue |
| I | HIS144 |
| I | PRO145 |
| I | ASP146 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL I 285 |
| Chain | Residue |
| C | HIS180 |
| I | HIS180 |
| I | HOH2480 |
| I | HOH3966 |
| site_id | CC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL J 283 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL J 284 |
| Chain | Residue |
| J | VAL49 |
| J | HIS115 |
| J | HOH2649 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL K 283 |
| Chain | Residue |
| K | LYS48 |
| K | VAL49 |
| K | HIS115 |
| K | HOH395 |
| K | HOH4077 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL K 284 |
| Chain | Residue |
| K | HIS144 |
| K | PRO145 |
| K | ASP146 |
| K | HOH4249 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL L 283 |
| Chain | Residue |
| L | HIS180 |
| V | HIS180 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL L 284 |
| Chain | Residue |
| L | LYS48 |
| L | VAL49 |
| L | HIS115 |
| L | HOH1028 |
| L | HOH1086 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL L 285 |
| Chain | Residue |
| L | HIS144 |
| L | ASP146 |
| L | LYS265 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL M 283 |
| Chain | Residue |
| M | HIS180 |
| X | HIS180 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL M 284 |
| Chain | Residue |
| M | LYS48 |
| M | VAL49 |
| M | HIS115 |
| M | HOH835 |
| M | HOH1038 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL M 285 |
| Chain | Residue |
| M | HIS144 |
| M | PRO145 |
| M | ASP146 |
| M | LYS265 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL N 283 |
| Chain | Residue |
| N | LYS48 |
| N | VAL49 |
| N | HIS115 |
| N | HOH754 |
| N | HOH956 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL N 284 |
| Chain | Residue |
| N | HIS144 |
| N | PRO145 |
| N | ASP146 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL N 285 |
| Chain | Residue |
| N | ALA179 |
| N | HIS180 |
| N | HOH762 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL O 283 |
| Chain | Residue |
| O | HIS180 |
| S | HIS180 |
| S | HOH3536 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL O 284 |
| Chain | Residue |
| O | LYS48 |
| O | VAL49 |
| O | HIS115 |
| O | HOH869 |
| O | HOH961 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL O 285 |
| Chain | Residue |
| O | HIS144 |
| O | PRO145 |
| O | ASP146 |
| O | LYS265 |
| site_id | EC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL P 283 |
| Chain | Residue |
| P | LYS48 |
| P | VAL49 |
| P | HIS115 |
| P | HOH780 |
| P | HOH970 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL P 284 |
| Chain | Residue |
| P | HIS144 |
| P | PRO145 |
| P | ASP146 |
| P | LYS265 |
| site_id | EC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL S 283 |
| site_id | EC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL S 284 |
| Chain | Residue |
| S | LYS48 |
| S | VAL49 |
| S | HIS115 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL S 285 |
| Chain | Residue |
| S | HIS144 |
| S | PRO145 |
| S | ASP146 |
| site_id | EC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL T 283 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL T 284 |
| Chain | Residue |
| T | LYS48 |
| T | VAL49 |
| T | HIS115 |
| T | HOH1220 |
| T | HOH3434 |
| site_id | FC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL T 285 |
| Chain | Residue |
| T | HIS144 |
| T | ASP146 |
| T | LYS265 |
| site_id | FC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL U 283 |
| Chain | Residue |
| U | LYS48 |
| U | VAL49 |
| U | HIS115 |
| U | HOH1137 |
| site_id | FC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL U 284 |
| Chain | Residue |
| U | HIS144 |
| U | PRO145 |
| U | ASP146 |
| site_id | FC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL U 285 |
| Chain | Residue |
| U | ALA179 |
| U | HIS180 |
| U | HOH1144 |
| site_id | FC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL V 283 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL V 284 |
| Chain | Residue |
| V | LYS48 |
| V | VAL49 |
| V | HIS115 |
| V | HOH1250 |
| V | HOH1325 |
| site_id | FC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL V 285 |
| Chain | Residue |
| V | HIS144 |
| V | PRO145 |
| V | ASP146 |
| V | HOH3198 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL X 283 |
| Chain | Residue |
| X | LYS48 |
| X | VAL49 |
| X | HIS115 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL X 284 |
| Chain | Residue |
| X | HIS144 |
| X | PRO145 |
| X | ASP146 |
| X | LYS265 |
| site_id | GC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL X 285 |
| site_id | GC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL a 283 |
| Chain | Residue |
| a | HIS180 |
| a | HOH3557 |
| j | HIS180 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL a 284 |
| Chain | Residue |
| a | LYS48 |
| a | VAL49 |
| a | GLY64 |
| a | HIS115 |
| a | HOH1748 |
| a | HOH1807 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL a 285 |
| Chain | Residue |
| a | HIS144 |
| a | PRO145 |
| a | ASP146 |
| a | LYS265 |
| site_id | GC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL b 283 |
| Chain | Residue |
| b | ALA179 |
| b | HIS180 |
| k | HIS180 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL b 284 |
| Chain | Residue |
| b | LYS48 |
| b | VAL49 |
| b | HIS115 |
| b | HOH1556 |
| b | HOH1759 |
| site_id | GC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL b 285 |
| Chain | Residue |
| b | HIS144 |
| b | ASP146 |
| b | LYS265 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL c 283 |
| Chain | Residue |
| c | LYS48 |
| c | VAL49 |
| c | HIS115 |
| c | HOH1469 |
| c | HOH1679 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL c 284 |
| Chain | Residue |
| c | HIS144 |
| c | PRO145 |
| c | ASP146 |
| c | LYS265 |
| site_id | HC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL c 285 |
| Chain | Residue |
| c | HIS180 |
| c | HOH4185 |
| i | HIS180 |
| site_id | HC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL d 283 |
| Chain | Residue |
| d | ALA179 |
| d | HIS180 |
| g | HIS180 |
| site_id | HC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL d 284 |
| Chain | Residue |
| d | LYS48 |
| d | VAL49 |
| d | HIS115 |
| d | HOH1589 |
| d | HOH1683 |
| site_id | HC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL d 285 |
| Chain | Residue |
| d | HIS144 |
| d | PRO145 |
| d | ASP146 |
| d | LYS265 |
| site_id | HC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL e 283 |
| Chain | Residue |
| e | LYS48 |
| e | VAL49 |
| e | HIS115 |
| e | HOH1494 |
| e | HOH1691 |
| site_id | HC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL e 284 |
| Chain | Residue |
| e | HIS180 |
| h | HIS180 |
| site_id | HC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL e 285 |
| Chain | Residue |
| e | HIS144 |
| e | PRO145 |
| e | ASP146 |
| e | LYS265 |
| site_id | HC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL g 283 |
| Chain | Residue |
| g | HIS180 |
| g | HOH2003 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL g 284 |
| Chain | Residue |
| g | LYS48 |
| g | VAL49 |
| g | HIS115 |
| g | HOH2073 |
| site_id | IC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL h 283 |
| site_id | IC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL h 284 |
| Chain | Residue |
| h | LYS48 |
| h | VAL49 |
| h | HIS115 |
| h | HOH2083 |
| site_id | IC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL h 285 |
| Chain | Residue |
| h | HIS144 |
| h | PRO145 |
| h | ASP146 |
| site_id | IC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL i 283 |
| Chain | Residue |
| i | LYS48 |
| i | VAL49 |
| i | HIS115 |
| i | HOH1855 |
| i | HOH2029 |
| site_id | IC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL i 284 |
| Chain | Residue |
| i | HIS144 |
| i | PRO145 |
| i | ASP146 |
| site_id | IC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL i 285 |
| Chain | Residue |
| i | HIS180 |
| i | HOH1861 |
| site_id | IC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL j 283 |
| Chain | Residue |
| a | HIS180 |
| j | HIS180 |
| site_id | IC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL j 284 |
| Chain | Residue |
| j | VAL49 |
| j | HIS115 |
| j | HOH1961 |
| site_id | JC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL j 285 |
| Chain | Residue |
| j | HIS144 |
| j | PRO145 |
| j | ASP146 |
| j | LYS265 |
| site_id | JC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL k 283 |
| Chain | Residue |
| k | LYS48 |
| k | VAL49 |
| k | HIS115 |
| k | HOH1879 |
| site_id | JC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL k 284 |
| Chain | Residue |
| j | HOH2034 |
| k | ASN4 |
| site_id | JC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL k 285 |
| Chain | Residue |
| b | HIS180 |
| k | HIS180 |
| site_id | JC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL k 286 |
| Chain | Residue |
| k | HIS144 |
| k | PRO145 |
| k | ASP146 |
