3N8K
Type II dehydroquinase from Mycobacterium tuberculosis complexed with citrazinic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019631 | biological_process | quinate catabolic process |
| B | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019631 | biological_process | quinate catabolic process |
| C | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019631 | biological_process | quinate catabolic process |
| D | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019631 | biological_process | quinate catabolic process |
| E | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| E | 0009423 | biological_process | chorismate biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019631 | biological_process | quinate catabolic process |
| F | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| F | 0009423 | biological_process | chorismate biosynthetic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0019631 | biological_process | quinate catabolic process |
| G | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| G | 0009423 | biological_process | chorismate biosynthetic process |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019631 | biological_process | quinate catabolic process |
| H | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| H | 0009423 | biological_process | chorismate biosynthetic process |
| H | 0016829 | molecular_function | lyase activity |
| H | 0019631 | biological_process | quinate catabolic process |
| I | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| I | 0005829 | cellular_component | cytosol |
| I | 0008652 | biological_process | amino acid biosynthetic process |
| I | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| I | 0009423 | biological_process | chorismate biosynthetic process |
| I | 0016829 | molecular_function | lyase activity |
| I | 0019631 | biological_process | quinate catabolic process |
| J | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| J | 0005829 | cellular_component | cytosol |
| J | 0008652 | biological_process | amino acid biosynthetic process |
| J | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| J | 0009423 | biological_process | chorismate biosynthetic process |
| J | 0016829 | molecular_function | lyase activity |
| J | 0019631 | biological_process | quinate catabolic process |
| K | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| K | 0005829 | cellular_component | cytosol |
| K | 0008652 | biological_process | amino acid biosynthetic process |
| K | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| K | 0009423 | biological_process | chorismate biosynthetic process |
| K | 0016829 | molecular_function | lyase activity |
| K | 0019631 | biological_process | quinate catabolic process |
| L | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| L | 0005829 | cellular_component | cytosol |
| L | 0008652 | biological_process | amino acid biosynthetic process |
| L | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| L | 0009423 | biological_process | chorismate biosynthetic process |
| L | 0016829 | molecular_function | lyase activity |
| L | 0019631 | biological_process | quinate catabolic process |
| M | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| M | 0005829 | cellular_component | cytosol |
| M | 0008652 | biological_process | amino acid biosynthetic process |
| M | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| M | 0009423 | biological_process | chorismate biosynthetic process |
| M | 0016829 | molecular_function | lyase activity |
| M | 0019631 | biological_process | quinate catabolic process |
| N | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| N | 0005829 | cellular_component | cytosol |
| N | 0008652 | biological_process | amino acid biosynthetic process |
| N | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| N | 0009423 | biological_process | chorismate biosynthetic process |
| N | 0016829 | molecular_function | lyase activity |
| N | 0019631 | biological_process | quinate catabolic process |
| O | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| O | 0005829 | cellular_component | cytosol |
| O | 0008652 | biological_process | amino acid biosynthetic process |
| O | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| O | 0009423 | biological_process | chorismate biosynthetic process |
| O | 0016829 | molecular_function | lyase activity |
| O | 0019631 | biological_process | quinate catabolic process |
| P | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| P | 0005829 | cellular_component | cytosol |
| P | 0008652 | biological_process | amino acid biosynthetic process |
| P | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| P | 0009423 | biological_process | chorismate biosynthetic process |
| P | 0016829 | molecular_function | lyase activity |
| P | 0019631 | biological_process | quinate catabolic process |
| Q | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| Q | 0005829 | cellular_component | cytosol |
| Q | 0008652 | biological_process | amino acid biosynthetic process |
| Q | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| Q | 0009423 | biological_process | chorismate biosynthetic process |
| Q | 0016829 | molecular_function | lyase activity |
| Q | 0019631 | biological_process | quinate catabolic process |
| R | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| R | 0005829 | cellular_component | cytosol |
| R | 0008652 | biological_process | amino acid biosynthetic process |
| R | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| R | 0009423 | biological_process | chorismate biosynthetic process |
| R | 0016829 | molecular_function | lyase activity |
| R | 0019631 | biological_process | quinate catabolic process |
| S | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| S | 0005829 | cellular_component | cytosol |
| S | 0008652 | biological_process | amino acid biosynthetic process |
| S | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| S | 0009423 | biological_process | chorismate biosynthetic process |
| S | 0016829 | molecular_function | lyase activity |
| S | 0019631 | biological_process | quinate catabolic process |
| T | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| T | 0005829 | cellular_component | cytosol |
| T | 0008652 | biological_process | amino acid biosynthetic process |
| T | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| T | 0009423 | biological_process | chorismate biosynthetic process |
| T | 0016829 | molecular_function | lyase activity |
| T | 0019631 | biological_process | quinate catabolic process |
| U | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| U | 0005829 | cellular_component | cytosol |
| U | 0008652 | biological_process | amino acid biosynthetic process |
| U | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| U | 0009423 | biological_process | chorismate biosynthetic process |
| U | 0016829 | molecular_function | lyase activity |
| U | 0019631 | biological_process | quinate catabolic process |
| V | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| V | 0005829 | cellular_component | cytosol |
| V | 0008652 | biological_process | amino acid biosynthetic process |
| V | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| V | 0009423 | biological_process | chorismate biosynthetic process |
| V | 0016829 | molecular_function | lyase activity |
| V | 0019631 | biological_process | quinate catabolic process |
| W | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| W | 0005829 | cellular_component | cytosol |
| W | 0008652 | biological_process | amino acid biosynthetic process |
| W | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| W | 0009423 | biological_process | chorismate biosynthetic process |
| W | 0016829 | molecular_function | lyase activity |
| W | 0019631 | biological_process | quinate catabolic process |
| X | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| X | 0005829 | cellular_component | cytosol |
| X | 0008652 | biological_process | amino acid biosynthetic process |
| X | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| X | 0009423 | biological_process | chorismate biosynthetic process |
| X | 0016829 | molecular_function | lyase activity |
| X | 0019631 | biological_process | quinate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X A 147 |
| Chain | Residue |
| A | ARG19 |
| A | ARG112 |
| A | HOH267 |
| L | ASP88 |
| A | TYR24 |
| A | ASN75 |
| A | GLY77 |
| A | GLY78 |
| A | HIS81 |
| A | HIS101 |
| A | ILE102 |
| A | SER103 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 148 |
| Chain | Residue |
| A | HIS106 |
| G | HIS106 |
| G | HOH255 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X B 147 |
| Chain | Residue |
| B | ARG19 |
| B | TYR24 |
| B | ASN75 |
| B | GLY77 |
| B | GLY78 |
| B | HIS81 |
| B | HIS101 |
| B | ILE102 |
| B | SER103 |
| B | ARG112 |
| B | HOH1502 |
| E | ASP88 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 148 |
| Chain | Residue |
| B | HIS106 |
| F | HIS106 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE D1X C 147 |
| Chain | Residue |
| B | ASP88 |
| B | HOH152 |
| C | PRO11 |
| C | ARG19 |
| C | TYR24 |
| C | ASN75 |
| C | GLY77 |
| C | GLY78 |
| C | HIS81 |
| C | HIS101 |
| C | ILE102 |
| C | SER103 |
| C | ARG112 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 148 |
| Chain | Residue |
| C | HIS106 |
| C | HOH415 |
| H | HIS106 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 149 |
| Chain | Residue |
| C | ALA95 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 150 |
| Chain | Residue |
| C | HOH151 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X D 147 |
| Chain | Residue |
| D | ARG19 |
| D | TYR24 |
| D | ASN75 |
| D | GLY77 |
| D | GLY78 |
| D | HIS81 |
| D | HIS101 |
| D | ILE102 |
| D | SER103 |
| D | ARG112 |
| D | HOH155 |
| G | ASP88 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 148 |
| Chain | Residue |
| D | HIS106 |
| I | HIS106 |
| I | HOH1535 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 149 |
| Chain | Residue |
| D | HOH1036 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 150 |
| Chain | Residue |
| D | ALA95 |
| D | THR122 |
| site_id | BC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X E 147 |
| Chain | Residue |
| C | ASP88 |
| C | HOH250 |
| E | ARG19 |
| E | TYR24 |
| E | ASN75 |
| E | GLY77 |
| E | GLY78 |
| E | HIS81 |
| E | HIS101 |
| E | ILE102 |
| E | SER103 |
| E | ARG112 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 148 |
| Chain | Residue |
| E | HIS106 |
| K | HIS106 |
| K | HOH1526 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL E 149 |
| Chain | Residue |
| E | ALA95 |
| site_id | BC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X F 147 |
| Chain | Residue |
| D | ASP88 |
| F | ARG19 |
| F | TYR24 |
| F | ASN75 |
| F | GLY77 |
| F | GLY78 |
| F | HIS81 |
| F | HIS101 |
| F | ILE102 |
| F | SER103 |
| F | ARG112 |
| F | HOH155 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL F 148 |
| Chain | Residue |
| F | THR122 |
| F | HOH1552 |
| site_id | BC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X G 147 |
| Chain | Residue |
| G | ASN75 |
| G | GLY77 |
| G | GLY78 |
| G | HIS81 |
| G | HIS101 |
| G | ILE102 |
| G | SER103 |
| G | ARG112 |
| F | ASP88 |
| F | HOH159 |
| G | ARG19 |
| G | TYR24 |
| site_id | CC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X H 147 |
| Chain | Residue |
| H | ARG19 |
| H | TYR24 |
| H | ASN75 |
| H | GLY77 |
| H | GLY78 |
| H | HIS81 |
| H | HIS101 |
| H | ILE102 |
| H | SER103 |
| H | ARG112 |
| H | HOH150 |
| J | ASP88 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL H 148 |
| Chain | Residue |
| H | ALA95 |
| H | THR122 |
| site_id | CC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE D1X I 147 |
| Chain | Residue |
| H | ASP88 |
| I | PRO11 |
| I | ARG19 |
| I | TYR24 |
| I | ASN75 |
| I | GLY77 |
| I | GLY78 |
| I | HIS81 |
| I | HIS101 |
| I | ILE102 |
| I | SER103 |
| I | ARG112 |
| I | HOH1503 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL I 148 |
| Chain | Residue |
| I | TYR24 |
| I | HOH1551 |
| site_id | CC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X J 147 |
| Chain | Residue |
| I | ASP88 |
| J | ARG19 |
| J | TYR24 |
| J | ASN75 |
| J | GLY77 |
| J | GLY78 |
| J | HIS81 |
| J | HIS101 |
| J | ILE102 |
| J | SER103 |
| J | ARG112 |
| J | HOH1504 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL J 148 |
| Chain | Residue |
| J | HIS106 |
| L | HIS106 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL J 149 |
| Chain | Residue |
| J | VAL23 |
| site_id | CC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X K 147 |
| Chain | Residue |
| A | ASP88 |
| A | HOH173 |
| K | ARG19 |
| K | TYR24 |
| K | ASN75 |
| K | GLY77 |
| K | GLY78 |
| K | HIS81 |
| K | HIS101 |
| K | ILE102 |
| K | SER103 |
| K | ARG112 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL K 148 |
| Chain | Residue |
| K | VAL23 |
| K | HOH1174 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL K 149 |
| Chain | Residue |
| K | THR122 |
| site_id | DC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE D1X L 147 |
| Chain | Residue |
| K | ASP88 |
| L | PRO11 |
| L | ARG19 |
| L | TYR24 |
| L | ASN75 |
| L | GLY77 |
| L | GLY78 |
| L | HIS81 |
| L | HIS101 |
| L | ILE102 |
| L | SER103 |
| L | ARG112 |
| L | HOH1505 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL L 148 |
| Chain | Residue |
| L | ALA95 |
| site_id | DC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL L 149 |
| Chain | Residue |
| L | VAL23 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL M 147 |
| Chain | Residue |
| M | HIS106 |
| S | HIS106 |
| site_id | DC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE D1X N 147 |
| Chain | Residue |
| N | ARG19 |
| N | TYR24 |
| N | ASN75 |
| N | GLY77 |
| N | GLY78 |
| N | HIS81 |
| N | ILE102 |
| N | SER103 |
| N | ARG112 |
| N | HOH1574 |
| site_id | DC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL N 148 |
| Chain | Residue |
| N | HIS106 |
| R | HIS106 |
| R | HOH1556 |
| site_id | DC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE D1X O 147 |
| Chain | Residue |
| N | ASP88 |
| O | ARG19 |
| O | TYR24 |
| O | ASN75 |
| O | GLY77 |
| O | HIS81 |
| O | HIS101 |
| O | ILE102 |
| O | SER103 |
| O | ARG112 |
| O | HOH1547 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL O 148 |
| Chain | Residue |
| O | HIS106 |
| O | HOH1561 |
| T | HIS106 |
| T | HOH1558 |
| site_id | EC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X P 147 |
| Chain | Residue |
| P | ARG19 |
| P | TYR24 |
| P | ASN75 |
| P | GLY77 |
| P | GLY78 |
| P | HIS81 |
| P | HIS101 |
| P | ILE102 |
| P | SER103 |
| P | ARG112 |
| P | HOH154 |
| S | ASP88 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL P 148 |
| Chain | Residue |
| P | HIS106 |
| P | HOH777 |
| U | HIS106 |
| site_id | EC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE D1X M 150 |
| Chain | Residue |
| M | ARG19 |
| M | TYR24 |
| M | ASN75 |
| M | GLY77 |
| M | HIS81 |
| M | HIS101 |
| M | ILE102 |
| M | SER103 |
| M | ARG112 |
| X | ASP88 |
| X | HOH391 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL Q 147 |
| Chain | Residue |
| Q | HIS106 |
| W | HIS106 |
| site_id | EC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X R 147 |
| Chain | Residue |
| P | ASP88 |
| P | HOH1507 |
| R | ARG19 |
| R | TYR24 |
| R | ASN75 |
| R | GLY77 |
| R | GLY78 |
| R | HIS81 |
| R | HIS101 |
| R | ILE102 |
| R | SER103 |
| R | ARG112 |
| site_id | EC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X S 147 |
| Chain | Residue |
| R | ASP88 |
| S | ARG19 |
| S | TYR24 |
| S | ASN75 |
| S | GLY77 |
| S | GLY78 |
| S | HIS81 |
| S | HIS101 |
| S | ILE102 |
| S | SER103 |
| S | ARG112 |
| S | HOH154 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL S 148 |
| Chain | Residue |
| S | GLY14 |
| S | HOH180 |
| S | HOH1264 |
| S | HOH1461 |
| site_id | EC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X T 147 |
| Chain | Residue |
| T | ARG19 |
| T | TYR24 |
| T | ASN75 |
| T | GLY77 |
| T | HIS81 |
| T | HIS101 |
| T | ILE102 |
| T | SER103 |
| T | VAL105 |
| T | ARG112 |
| V | ASP88 |
| V | HOH395 |
| site_id | EC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE D1X U 147 |
| Chain | Residue |
| T | ASP88 |
| T | HOH1508 |
| U | ARG19 |
| U | TYR24 |
| U | ASN75 |
| U | GLY77 |
| U | HIS81 |
| U | HIS101 |
| U | ILE102 |
| U | SER103 |
| U | ARG112 |
| site_id | FC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X V 147 |
| Chain | Residue |
| U | ASP88 |
| V | ARG19 |
| V | TYR24 |
| V | ASN75 |
| V | GLY77 |
| V | GLY78 |
| V | HIS81 |
| V | HIS101 |
| V | ILE102 |
| V | SER103 |
| V | ARG112 |
| V | HOH1548 |
| site_id | FC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL V 148 |
| Chain | Residue |
| V | HIS106 |
| X | HIS106 |
| X | VAL126 |
| site_id | FC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE D1X W 147 |
| Chain | Residue |
| M | ASP88 |
| W | ARG19 |
| W | TYR24 |
| W | ASN75 |
| W | GLY77 |
| W | GLY78 |
| W | HIS81 |
| W | HIS101 |
| W | ILE102 |
| W | SER103 |
| W | ARG112 |
| W | HOH441 |
Functional Information from PROSITE/UniProt
| site_id | PS01029 |
| Number of Residues | 18 |
| Details | DEHYDROQUINASE_II Dehydroquinase class II signature. INGPNLgrLGrREpavYG |
| Chain | Residue | Details |
| A | ILE8-GLY25 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | TYR24 | |
| J | TYR24 | |
| K | TYR24 | |
| L | TYR24 | |
| M | TYR24 | |
| N | TYR24 | |
| O | TYR24 | |
| P | TYR24 | |
| Q | TYR24 | |
| R | TYR24 | |
| S | TYR24 | |
| B | TYR24 | |
| T | TYR24 | |
| U | TYR24 | |
| V | TYR24 | |
| W | TYR24 | |
| X | TYR24 | |
| C | TYR24 | |
| D | TYR24 | |
| E | TYR24 | |
| F | TYR24 | |
| G | TYR24 | |
| H | TYR24 | |
| I | TYR24 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | HIS101 | |
| J | HIS101 | |
| K | HIS101 | |
| L | HIS101 | |
| M | HIS101 | |
| N | HIS101 | |
| O | HIS101 | |
| P | HIS101 | |
| Q | HIS101 | |
| R | HIS101 | |
| S | HIS101 | |
| B | HIS101 | |
| T | HIS101 | |
| U | HIS101 | |
| V | HIS101 | |
| W | HIS101 | |
| X | HIS101 | |
| C | HIS101 | |
| D | HIS101 | |
| E | HIS101 | |
| F | HIS101 | |
| G | HIS101 | |
| H | HIS101 | |
| I | HIS101 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 120 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASN75 | |
| B | ARG112 | |
| T | ARG112 | |
| U | ASN75 | |
| U | HIS81 | |
| U | ASP88 | |
| U | ILE102 | |
| U | ARG112 | |
| V | ASN75 | |
| V | HIS81 | |
| V | ASP88 | |
| V | ILE102 | |
| C | ASN75 | |
| V | ARG112 | |
| W | ASN75 | |
| W | HIS81 | |
| W | ASP88 | |
| W | ILE102 | |
| W | ARG112 | |
| X | ASN75 | |
| X | HIS81 | |
| X | ASP88 | |
| X | ILE102 | |
| C | HIS81 | |
| X | ARG112 | |
| C | ASP88 | |
| C | ILE102 | |
| C | ARG112 | |
| D | ASN75 | |
| D | HIS81 | |
| D | ASP88 | |
| D | ILE102 | |
| A | HIS81 | |
| D | ARG112 | |
| E | ASN75 | |
| E | HIS81 | |
| E | ASP88 | |
| E | ILE102 | |
| E | ARG112 | |
| F | ASN75 | |
| F | HIS81 | |
| F | ASP88 | |
| F | ILE102 | |
| A | ASP88 | |
| F | ARG112 | |
| G | ASN75 | |
| G | HIS81 | |
| G | ASP88 | |
| G | ILE102 | |
| G | ARG112 | |
| H | ASN75 | |
| H | HIS81 | |
| H | ASP88 | |
| H | ILE102 | |
| A | ILE102 | |
| H | ARG112 | |
| I | ASN75 | |
| I | HIS81 | |
| I | ASP88 | |
| I | ILE102 | |
| I | ARG112 | |
| J | ASN75 | |
| J | HIS81 | |
| J | ASP88 | |
| J | ILE102 | |
| A | ARG112 | |
| J | ARG112 | |
| K | ASN75 | |
| K | HIS81 | |
| K | ASP88 | |
| K | ILE102 | |
| K | ARG112 | |
| L | ASN75 | |
| L | HIS81 | |
| L | ASP88 | |
| L | ILE102 | |
| B | ASN75 | |
| L | ARG112 | |
| M | ASN75 | |
| M | HIS81 | |
| M | ASP88 | |
| M | ILE102 | |
| M | ARG112 | |
| N | ASN75 | |
| N | HIS81 | |
| N | ASP88 | |
| N | ILE102 | |
| B | HIS81 | |
| N | ARG112 | |
| O | ASN75 | |
| O | HIS81 | |
| O | ASP88 | |
| O | ILE102 | |
| O | ARG112 | |
| P | ASN75 | |
| P | HIS81 | |
| P | ASP88 | |
| P | ILE102 | |
| B | ASP88 | |
| P | ARG112 | |
| Q | ASN75 | |
| Q | HIS81 | |
| Q | ASP88 | |
| Q | ILE102 | |
| Q | ARG112 | |
| R | ASN75 | |
| R | HIS81 | |
| R | ASP88 | |
| R | ILE102 | |
| B | ILE102 | |
| R | ARG112 | |
| S | ASN75 | |
| S | HIS81 | |
| S | ASP88 | |
| S | ILE102 | |
| S | ARG112 | |
| T | ASN75 | |
| T | HIS81 | |
| T | ASP88 | |
| T | ILE102 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | SITE: Transition state stabilizer |
| Chain | Residue | Details |
| A | ARG19 | |
| J | ARG19 | |
| K | ARG19 | |
| L | ARG19 | |
| M | ARG19 | |
| N | ARG19 | |
| O | ARG19 | |
| P | ARG19 | |
| Q | ARG19 | |
| R | ARG19 | |
| S | ARG19 | |
| B | ARG19 | |
| T | ARG19 | |
| U | ARG19 | |
| V | ARG19 | |
| W | ARG19 | |
| X | ARG19 | |
| C | ARG19 | |
| D | ARG19 | |
| E | ARG19 | |
| F | ARG19 | |
| G | ARG19 | |
| H | ARG19 | |
| I | ARG19 |
