3N6Q

Crystal structure of YghZ from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006974	biological_process	DNA damage response
A	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0051596	biological_process	methylglyoxal catabolic process
A	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
B	0006974	biological_process	DNA damage response
B	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0051596	biological_process	methylglyoxal catabolic process
B	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
C	0006974	biological_process	DNA damage response
C	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0051596	biological_process	methylglyoxal catabolic process
C	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
D	0006974	biological_process	DNA damage response
D	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0051596	biological_process	methylglyoxal catabolic process
D	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
E	0006974	biological_process	DNA damage response
E	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0051596	biological_process	methylglyoxal catabolic process
E	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
F	0006974	biological_process	DNA damage response
F	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0051596	biological_process	methylglyoxal catabolic process
F	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
G	0006974	biological_process	DNA damage response
G	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
G	0016491	molecular_function	oxidoreductase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0051596	biological_process	methylglyoxal catabolic process
G	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity
H	0006974	biological_process	DNA damage response
H	0008106	molecular_function	alcohol dehydrogenase (NADP+) activity
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0051596	biological_process	methylglyoxal catabolic process
H	1990002	molecular_function	methylglyoxal reductase (NADPH) (acetol producing) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	ARG79
A	GLU83
A	HOH922
F	HIS38
F	GLU75

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	GLU83
B	HOH821
G	HIS38
G	GLU75

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	GLU83
C	HOH770
H	HIS38
H	GLU75

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 401

Chain	Residue
D	GLU83
D	HOH772
E	HIS38
E	GLU75

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 402

Chain	Residue
D	HIS38
D	GLU75
E	GLU83
E	MG401
E	HOH616

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
D	HIS38
D	GLU75
D	MG402
E	GLU83

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 401

Chain	Residue
A	HIS38
A	GLU75
F	GLU83

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG G 401

Chain	Residue
B	HIS38
B	GLU75
G	GLU83

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG H 401

Chain	Residue
C	HIS38
C	GLU75
H	GLU83

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23103600","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Site: {"description":"Important for catalysis","evidences":[{"source":"PubMed","id":"22393408","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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