Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004517 | molecular_function | nitric-oxide synthase activity |
A | 0006809 | biological_process | nitric oxide biosynthetic process |
B | 0004517 | molecular_function | nitric-oxide synthase activity |
B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE HEM A 750 |
Chain | Residue |
A | TRP409 |
A | GLU592 |
A | ARG596 |
A | TRP678 |
A | TYR706 |
A | XFN800 |
A | ACT860 |
A | HOH1004 |
A | HOH1021 |
A | HOH1044 |
A | HOH1053 |
A | ARG414 |
A | CYS415 |
A | VAL416 |
A | SER457 |
A | PHE584 |
A | SER585 |
A | TRP587 |
A | MET589 |
site_id | AC2 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE XFN A 800 |
Chain | Residue |
A | VAL336 |
A | ARG481 |
A | VAL567 |
A | PHE584 |
A | TRP587 |
A | GLU592 |
A | ARG596 |
A | VAL677 |
A | TRP678 |
A | HEM750 |
A | CL910 |
A | HOH1015 |
A | HOH1034 |
A | HOH1086 |
B | PHE691 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE ACT A 860 |
Chain | Residue |
A | TRP587 |
A | HEM750 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 900 |
Chain | Residue |
A | CYS326 |
A | CYS331 |
B | CYS326 |
B | CYS331 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 901 |
Chain | Residue |
A | ASP600 |
A | CL910 |
B | HIS692 |
B | HOH1269 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL A 910 |
Chain | Residue |
A | ARG596 |
A | ASP600 |
A | XFN800 |
A | ZN901 |
A | HOH1033 |
B | HIS692 |
site_id | AC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 930 |
Chain | Residue |
A | GLN478 |
A | TYR588 |
A | ARG596 |
A | ASN597 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 719 |
Chain | Residue |
A | HIS692 |
A | HOH1113 |
B | ASP600 |
B | CL910 |
site_id | AC9 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE HEM B 750 |
Chain | Residue |
B | TRP409 |
B | ARG414 |
B | CYS415 |
B | PHE584 |
B | SER585 |
B | GLY586 |
B | TRP587 |
B | MET589 |
B | GLU592 |
B | ARG596 |
B | TRP678 |
B | PHE704 |
B | TYR706 |
B | XFN800 |
B | ACT860 |
B | HOH1124 |
B | HOH1157 |
B | HOH1187 |
site_id | BC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE XFN B 800 |
Chain | Residue |
A | PHE691 |
B | VAL336 |
B | ARG481 |
B | VAL567 |
B | PHE584 |
B | TRP587 |
B | GLU592 |
B | ARG596 |
B | VAL677 |
B | TRP678 |
B | HEM750 |
B | CL910 |
B | HOH1190 |
B | HOH1233 |
B | HOH1257 |
B | HOH1267 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ACT B 860 |
Chain | Residue |
B | GLY417 |
B | TRP587 |
B | HEM750 |
B | HOH1201 |
site_id | BC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE CL B 910 |
Chain | Residue |
A | HOH1113 |
B | ARG596 |
B | ASP600 |
B | XFN800 |
A | HIS692 |
A | ZN719 |
A | HOH1068 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL B 930 |
Chain | Residue |
B | GLN478 |
B | TYR588 |
B | ARG596 |
B | ASN597 |
B | HOH1221 |
Functional Information from PROSITE/UniProt
site_id | PS60001 |
Number of Residues | 8 |
Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
Chain | Residue | Details |
A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER334 | |
B | SER334 | |
B | GLN478 | |
B | TRP587 | |
B | TYR588 | |
B | GLU592 | |
B | VAL677 | |
B | TRP678 | |
B | PHE691 | |
B | TYR706 | |
A | GLN478 | |
A | TRP587 | |
A | TYR588 | |
A | GLU592 | |
A | VAL677 | |
A | TRP678 | |
A | PHE691 | |
A | TYR706 | |
Chain | Residue | Details |
A | CYS415 | |
B | CYS415 | |