Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | TRP409 |
| A | ARG596 |
| A | TRP678 |
| A | PHE704 |
| A | XFJ800 |
| A | HOH1015 |
| A | HOH1041 |
| A | HOH1107 |
| B | H4B760 |
| B | XFJ805 |
| A | CYS415 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| A | MET589 |
| A | GLU592 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE XFJ A 800 |
| Chain | Residue |
| A | LEU337 |
| A | ARG414 |
| A | GLN478 |
| A | VAL567 |
| A | PHE584 |
| A | TRP587 |
| A | GLU592 |
| A | ARG596 |
| A | TYR706 |
| A | HEM750 |
| A | HOH1069 |
| A | HOH1122 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 860 |
| Chain | Residue |
| A | TRP587 |
| A | SER657 |
| A | HOH1092 |
| A | HOH1119 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MTL A 870 |
| Chain | Residue |
| A | SER477 |
| A | ARG481 |
| A | ALA497 |
| A | ASN498 |
| A | GLN500 |
| A | PHE501 |
| A | ASN569 |
| A | ASP709 |
| A | HOH1032 |
| B | XFJ805 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 910 |
| Chain | Residue |
| A | ARG596 |
| A | ASP600 |
| A | ZN901 |
| B | SER686 |
| B | HIS692 |
| B | XFJ805 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 901 |
| Chain | Residue |
| A | ASP600 |
| A | CL910 |
| A | HOH920 |
| B | HIS692 |
| B | XFJ805 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H4B A 760 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| A | HOH1077 |
| B | SER334 |
| B | MET336 |
| B | VAL677 |
| B | TRP678 |
| B | XFJ719 |
| B | HEM750 |
| B | HOH921 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 719 |
| Chain | Residue |
| A | HIS692 |
| B | ASP600 |
| B | XFJ719 |
| B | CL910 |
| B | HOH920 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE H4B B 760 |
| Chain | Residue |
| A | SER334 |
| A | MET336 |
| A | VAL677 |
| A | TRP678 |
| A | HEM750 |
| A | HOH921 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| B | XFJ805 |
| B | HOH1250 |
| site_id | BC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE XFJ B 805 |
| Chain | Residue |
| B | TRP306 |
| B | ASP309 |
| B | PHE691 |
| B | HIS692 |
| B | H4B760 |
| A | ARG596 |
| A | ASP600 |
| A | VAL677 |
| A | TRP678 |
| A | HEM750 |
| A | MTL870 |
| A | ZN901 |
| A | CL910 |
| A | HOH920 |
| A | HOH921 |
| site_id | BC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| A | H4B760 |
| B | TRP409 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | ARG596 |
| B | TRP678 |
| B | PHE704 |
| B | XFJ719 |
| B | XFJ800 |
| B | HOH1212 |
| B | HOH1329 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE XFJ B 800 |
| Chain | Residue |
| B | ARG414 |
| B | GLN478 |
| B | VAL567 |
| B | PHE584 |
| B | TRP587 |
| B | GLU592 |
| B | ARG596 |
| B | HEM750 |
| B | MTL870 |
| B | HOH1277 |
| B | HOH1334 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE XFJ B 719 |
| Chain | Residue |
| A | TRP306 |
| A | ASP309 |
| A | PHE691 |
| A | HIS692 |
| A | ZN719 |
| A | H4B760 |
| B | ARG596 |
| B | ASP600 |
| B | VAL677 |
| B | TRP678 |
| B | HEM750 |
| B | MTL870 |
| B | CL910 |
| B | HOH920 |
| B | HOH921 |
| B | HOH1199 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 860 |
| Chain | Residue |
| B | TRP587 |
| B | VAL649 |
| B | HOH1262 |
| B | HOH1263 |
| B | HOH1289 |
| B | HOH1335 |
| site_id | BC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MTL B 870 |
| Chain | Residue |
| B | SER477 |
| B | ARG481 |
| B | ALA497 |
| B | ASN498 |
| B | GLN500 |
| B | PHE501 |
| B | ASN569 |
| B | ASP709 |
| B | XFJ719 |
| B | XFJ800 |
| B | HOH1274 |
| B | HOH1307 |
| B | HOH1388 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 910 |
| Chain | Residue |
| A | SER686 |
| A | ZN719 |
| B | ARG596 |
| B | ASP600 |
| B | XFJ719 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
