3N5O
Crystal structure of putative glutathione transferase from Coccidioides immitis bound to glutathione
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GSH A 232 |
| Chain | Residue |
| A | SER14 |
| A | SER81 |
| A | GLN124 |
| A | ASN128 |
| A | LEU129 |
| A | LYS130 |
| A | SO4233 |
| A | HOH252 |
| A | HOH517 |
| A | HOH619 |
| B | CYS121 |
| A | SER15 |
| B | ASP122 |
| B | HOH499 |
| B | HOH554 |
| A | CYS16 |
| A | ARG19 |
| A | GLN43 |
| A | THR56 |
| A | VAL57 |
| A | PRO58 |
| A | GLN80 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 233 |
| Chain | Residue |
| A | ARG13 |
| A | SER14 |
| A | SER15 |
| A | GLN124 |
| A | ASN128 |
| A | GSH232 |
| A | HOH333 |
| A | HOH334 |
| A | HOH524 |
| A | HOH661 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 233 |
| Chain | Residue |
| B | SER14 |
| B | SER15 |
| B | GLN124 |
| B | ASN128 |
| B | HOH406 |
| B | HOH421 |
| B | HOH574 |
| B | HOH649 |
| B | HOH650 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 693 |
| Chain | Residue |
| B | ASN64 |
| B | ILE65 |
| B | THR94 |
| B | HOH480 |
| B | HOH485 |
| B | HOH621 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| A | SER14 | |
| A | GLN43 | |
| A | VAL57 | |
| A | GLN124 | |
| B | SER14 | |
| B | GLN43 | |
| B | VAL57 | |
| B | GLN124 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLN80 | |
| A | ASN128 | |
| B | GLN80 | |
| B | ASN128 |
